Adult - Derm Flashcards

(70 cards)

1
Q

What is the most common of all skin disorders?

A

acne

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2
Q

Which acne symptoms are red flags that indicate the need for referral?

A
  • scarring
  • cyst formation
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3
Q

First line (non-pharmocologic) treatment for acne

A

wash several times daily with mild soap

use oil-free products

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4
Q

What is the order of pharmacologic treatment in acne?

A
  1. comedolytics
  2. topical combination agents: comedolytic + ABT
  3. topical antibiotics
  4. oral antibiotics
  5. oral contraceptives
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5
Q

First line pharmacologic treatment for acne

A

comedolytics:

benzoyl peroxide - bacteriocidal

trentoin (Retin-A)

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6
Q

What is a potential side effect of retin-a (tretinoin)?

A

Increased sensitivity to sunlight

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7
Q

What is the second pharmacologic step in acne treatment?

A

combination agents:

benzoyl peroxide + erythromycin = Benzamycin

benzoyl peroxide + clindamycin = Benzaclin

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8
Q

What is the third pharmacologic step of acne management?

A

topical antibiotics:

clindamycin

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9
Q

What is the** fourth** pharmacologic step of acne management?

A

Oral antibiotics:

tetracycline

why is tetracycline contraindicated in pregnancy and children under 9 years?

due to staining of teeth

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10
Q

What is the** fifth** pharmacologic step of acne management?

A

oral contraceptives:

combination products are most effective

ortho tri-cyclen or estrostep

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11
Q

What is a derm-related side effect of oral contraceptive therapy?

A

melasma - brown splotches on the skin

as opposed to the “mask of pregnancy” which is known as:

chloasma

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12
Q

What are two additional therapies that could be used for acne treatment, though not in primary care?

A

dermabrasion

intralesional injections of the steroid triamcinolone

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13
Q

Which two pathogens are the “major players” in skin infections in the community?

A

staph aureus

strep (usually Group A)

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14
Q

Inflammation of the hair follicle -

term and pathogen

A

folliculitis

staph

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15
Q

Localized infection originating from the hair follicle but now more involved -

term and pathogen

A

furuncle

“boil”

staph

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16
Q

What does a CA-MRSA furuncle look like?

A

A spider bite

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17
Q

A red, swollen, and painful cluster of boils that are connected to each other under the skin -

term and pathogen

A

carbuncle

staph

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18
Q

What are the common causes of cellulitis in the community?

A
  1. Strep pyogenes (Group A) - usual cause
  2. Staph aureus - less common
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19
Q

What are the common causes of cellulits in the inpatient population?

A

Gram NEGATIVE organisms -

E. coli

Klebsiella

Psuedomonas

Enterobacter

less frequently - Gram POSITIVE organisms

MRSA? CA-MRSA?

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20
Q

In the outpatient, what 3 drugs can be used to treat CA-MRSA cellulitis?

A
  • Bactrim (TMP/SMZ)
  • Doxyclycline / minocyline
  • Clindamycin

Which of these also covers Group A strep?

Clindamycin

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21
Q

What additional drug class must be aded to Bactrim or Doxycyline / Minocycline in order to provide Group A strep coverage?

A

a beta lactam

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22
Q

What are some examples of the beta lactams?

A

penicillin

amoxicillin

1st generation cephalosporin (Keflex)

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23
Q

What cellulitis-treating antibiotic provides coverage for both staph and strep?

A

Clindamycin

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24
Q

An acute infection of the upper dermis and superficial lymphatics; more superficial than cellulitis, typically more raised and demarcated

“look’s like big sunburn”

  • condition and pathogen
A

Erysipelas

Strep

Known for insidious or rapid progression?

rapid

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25
Infection and abcess formation, typically in the axilla or groin - condition and pathogen
Hidradenitis suppurativa staph
26
Characterized by honey colored crusts on an erythematous base - condition and pathogen
Impetigo staph
27
Infection of the skin around the finger or toe nail - term and pathogen
**paronychia** staph
28
Collection of blood between the fingernail and nail bed - term and management
**subungual hematoma** **trephination** - drilling a hole through the nail to relieve the pressure
29
candida **balanitis - ** location?
candida of the penile head
30
candida **intertrigo -** location?
candida in warm, moist folds of skin
31
For most candida, what is management?
topical antifungals first oral antifungals only if topicals unsuccessful
32
Four examples of antifungals?
miconazole clotrimazole fluconazole griseofulvin
33
What are two fungal infections which are treated with selenium shampoo?
tinea capitus tinea versicolor
34
Another name for herpes zoster is:
shingles
35
Pharm options for herpes zoster have what suffix?
-cyclovir
36
What is a red flag in herpes zoster?
**eye or face** involvement - ## Footnote ** refer right away**
37
What medications can be used for post-herpetic neuralgia?
gabapentin (Neurontin) pregabalin (Lyrica)
38
What are two significant side effects of gabapentin and pregabalin?
excessive sleep significant weight gain
39
What vaccine can be used to prevent or mitigate herpes zoster? approved starting at what age?
zostavax age 50
40
What are pre-malignant, small, rough patches on sun-exposed parts of the body?
actinic keratosis
41
What type of skin cancer arises from actinic keratosis?
squamous cell carcinoma
42
How is actinic keratoses treated?
liquid nitrogen
43
What lesions are the precursors to squamous cell carcinoma?
actinic keratosis
44
How long does it take for squamous cell carcinoma to develop from an AK?
over a few months
45
Description of squamous cell carcinoma
firm, irregular papule or nodule with keratictic, scaly bleeding (yum)
46
Treatment for squamous cell carcinoma
refer for: biopsy Mohs excision
47
Benign, beige to black plaque, with a "stuck-on" appearance.
seborrheic keratosis
48
Treatment in seborrheic keratoses
liquid nitrogen or none
49
What is the most common type of skin cancer?
basal cell carcinoma
50
Waxy, pearly, shiny lesion with central depression or rolled edge, and possibly with telangiectatic vessels.
basal cell carcinoma
51
What is the treatment for basal cell carcinoma?
shave or punch biopsy and surgical excision
52
Which skin cancer has the highest mortality rate?
melanoma
53
What are the ABCs to remember with melanoma?
A - asymmetry B - border irrecularity C - color variation D - diameter \> 6 mm E - elevation E - enlargement
54
What is an important detail to teach patients about applying steriods to their atopic dermatitis?
it is most effective when rubbed in very well
55
What might be the underlying cause of an explosive onset derm disorder that an adult has never previously had?
HIV infection
56
What is the only derm disorder for which tar shampoo is recommended?
psoriasis
57
Yellow plaques as a result of fat build up under skin; often near inner canthus.
Xanthelasma **what is underlying cause?** hyperlipidemia
58
What is the hallmark rash of Lyme disease?
erythema migrans
59
What is the initial test for Lyme disease? confirmatory?
ELISA Western blot (same as HIV)
60
What antibiotics are used for Lyme disease?
Doxycyline Amoxicillin
61
What is the typical rash in Rocky Mountain Spotted fever?
maculo-papular petechial
62
What is the testing for Rocky Mountain Spotted fever?
PCR (like infant HIV test)
63
What is the treatment for Rocky Mountain Spotted Fever?
Doxycycline
64
Hallmark distribution of smallpox lesions -
first lesions on face, palate, oral mucosa spread from there on any one part of the body, all lesions are at the same stage
65
What is the causative agent of anthrax?
**bacteria**, though often referred to as "spores"
66
Is there a vaccine for anthrax?
yes
67
What are the two types of anthrax infections?
cutaneous inhalation
68
What is the progression of the cutaneous form of anthrax?
pruritic papule ulcer surrounded by vesicles black necrotic eschar with edema eschar falls off leaving scar
69
What is used to treat anthrax?
PCN ciprofloxacin (Cipro) doxycyline
70
Treatment options for genital warts:
* **podophyllin** resin * **podofilox (Condylox)** * **cryosurgery** * **TCA** - trichloroacetic acid * **BCA** - bichloracetic acid