DNA Viruses (cont.)

Question 1

What are the DNA viruses?

Answer 1

HHAPPPy

• Herpesvirus
• Hepadnavirus
• Adenovirus
• Papovavirus
• Parvovirus
• Poxvirus

Question 2

What does Adenovirus cause?

Answer 2

A cold

- sore throat, rhinorrhea, cough, malaise

Question 3

DNA virus that causes a cold?

Answer 3

Adenovirus

Question 4

3 Papovaviruses?

Answer 4

Human Papilloma Virus (HPV)
BK Polyoma Virus
JC Polyoma Virus

Question 5

3 Papovaviruses?

Answer 5

Human Papilloma Virus (HPV)
BK Polyoma Virus
JC Polyoma Virus

Question 6

What does the Human Papilloma Virus cause?

Answer 6

Common and genital warts

Question 7

What proteins in the Human Papilloma Virus interfere with the tumor suppressor genes?

Answer 7

E6 and E7

Question 8

If E6 and E7 proteins with Human Papilloma Virus interfere with tumor suppressor genes, what will that cause?

Answer 8

Epithelial Dysplasia

Question 9

What can Epithelial Dysplasia result in?

Answer 9

Carcinoma

Question 10

What are the high risk strains that can cause cervical cancer from the Human Papilloma Virus?

Answer 10

16, 18, 31, 45

Question 11

What test catches cervical cancer from Human Papilloma Virus at the dysplasia/carcinoma stage?

Answer 11

Pap smear

Question 12

In what patient population can BK and JC Polyomavirus cause disease?

Answer 12

Immunocompromised

Question 13

BK polyomavirus causes disease in ____ patients

Answer 13

Renal transplant

Question 14

Symptoms of BK Polyomavirus infection?

Answer 14

Ground glass inclusions in the bladder and kidney

Question 15

JC Polyomavirus causes disease ___ patients

Answer 15

AIDS

Question 16

Symptoms of JC Polyomavirus infection?

Answer 16

Progressive Multifocal Leukoencephalopathy
= Demyelinating CNS
== Speech, behavior, motor problems

Question 17

Parvovirus B19 causes what main symptoms in a child?

Answer 17

Rash slapped cheeks (erythema infectiosum), low fever, headache

Question 18

Rash slapped cheeks

Answer 18

Parvovirus B19

Question 19

If Parvovirus B19 causes a transient aplastic crisis what does the virus do?

Answer 19

Infects RBC precursors (reticulocytes)

Question 20

A transient aplastic crisis due to parvovirus B19 that is temporary causes?

Answer 20

Decrease in RBC production that will return to normal

Question 21

A transient aplastic crisis due to parvovirus B19 in child with sickle cell or thalassemia will cause?

Answer 21

Severe anemia, fetal hydrops and death

Question 22

What are the Poxvirus members?

Answer 22

Molluscum Contagiosum

Smallpox

Question 23

Molluscum Contagiosum and Smallpox are members of what virus?

Answer 23

Poxvirus

Question 24

Who is at risk for infection with Molluscum Contagiosum?

Answer 24

Children and HIV patients

Question 25

Symptoms of infection with Molluscum Contagiosum?

Answer 25

Dome lesions with center dimple all over the body

Question 26

Symptoms of infection with Smallpox?

Answer 26

Fever and hard vesicles all in same stage of development

Question 27

Hard vesicles all in the same stage of development

Answer 27

Smallpox