Gram (-) Bacteria - Respiratory and Zoonotic Bacilli

Question 1

What are 3 respiratory pathogens?

Answer 1

Bordetella Pertussis
Legionella Pneumophila
Haemophilus Influenzae

Question 2

What are 3 respiratory pathogens?

Answer 2

Bordetella Pertussis
Legionella Pneumophila
Haemophilus Influenzae

Question 3

What toxin is involved with Bordetella Pertussis?

Answer 3

Pertussis Toxin

Question 4

What does the Pertussis Toxin increase and decrease?

Answer 4

Increases CAMP and Histamine

Decreases phagocytosis

Question 5

Cascade of symptoms with Bordetella Pertussis?

Answer 5

Cold - sneezing, rhinorrhea, fever
1-2 weeks later
Whooping cough
Can then progress to pneumonia

Question 6

Describe a whooping cough and what is it seen with?

Answer 6

Hacking cough followed by a high pitched inspiratory whoop

– Seen with Bordetella Pertussis

Question 7

Where is Legionella Pneumophila found?

Answer 7

Water systems

Question 8

What 2 diseases are a consequence of Legionella Pneumophila?

Answer 8

Pontiac Fever

Legionnaire’s Disease

Question 9

Pontiac Fever

Answer 9

• Consequence of Legionella Pneumophila

= Self - limited Febrile illness - 2-5 days

Question 10

Legionnaire’s Disease

Answer 10

• More severe consequence of Legionella Pneumophila

= Multilobar pneumonia with abscess

Question 11

Haemophilus Influenzae - encapsulated or nonencaspsulated version is more dangerous?

Answer 11

Encapsulated - due to capsule protecting from phagocytosis

Question 12

What does Haemophilus Influenzae require for growth in the blood?

Answer 12

Hemin and NAD (X and V factors)

Question 13

What vaccination is important in infant life for Haemophilus Influenzae?

Answer 13

Hib

Question 14

Symptoms of infection with encapsulated Haemophilus Influenzae?

Answer 14

Early childhood meningitis
Acute epiglottitis (drooling, sore throat, wheezing)

Question 15

Symptoms of infection with nonencapsulated Haemophilus Influenzae?

Answer 15

Otitis Media

Question 16

Other Gram (-) bacteria associated with genital presentations?

Answer 16

Chancroid

Gardnerella Vaginalis

Question 17

What factors are required for growth of Chancroid (Haemophilus Ducreyi)?

Answer 17

Hemin and NAD (X and V factors)

Question 18

Chancroid - Haemophilus Ducreyi is a _____ disease

Answer 18

Sexually transmitted disease

Question 19

What are the 2 symptoms of infection with Chancroid - Haemophilus Ducreyi?

Answer 19

PAINFUL genital ulcer

PAINFUL pus forming lymphadenopathy

Question 20

What other sexually transmitted disease has painful genital ulcers but NO pus forming lymphadenopathy to separate it from Chancroid?

Answer 20

Herpes

Question 21

What causes Bacterial Vaginitis?

Answer 21

Gardnerella Vaginalis

Question 22

What type of cells are detected on pap smear to indicate Gardnerella Vaginalis?

Answer 22

Clue cells

Question 23

Symptoms of infection with Gardnerella Vaginalis?

Answer 23

Fishy smelling discharge

Pruritus and Dysuria

Question 24

List 5 Zoonotic Bacilli

Answer 24

Yersinia Pestis
Francisella Tularensis
Brucella Species
Pasturella Multocida
Bartonella Species

Question 25

What shape is Yersinia Pestis?

Answer 25

Safety pin - bipolar shape

Question 26

Describe how people become infected with Yersinia Pestis

Answer 26

Prairie dogs and wild rodents --> Fleas --> People

Question 27

What plagues are associated with Yersinia Pestis?

Answer 27

Bubonic Plague | Pneumonic Plague

Question 28

Symptoms of Bubonic Plague

Answer 28

- Yersinia Pestis | = Hemorrhage under skin, hot painful lymph nodes, fever

Question 29

Pneumonic Plague is what ____ is spread to ____ from ____

Answer 29

Bubonic Plague is spread to humans from humans

Question 30

In what animals is Francisella Tularensis found?

Answer 30

Rabbits, tick or deerflies

Question 31

Symptoms of infection with Francisella Tularensis?

Answer 31

Similar to Bubonic plague - hemorrhage under skin, hot painful lymph nodes and SKIN ULCER

Question 32

In what animal produces is Brucella Species found?

Answer 32

Domesticated animal products - unpasteurized milk, meat, placenta -- cows, goats, pigs

Question 33

Unique symptoms of infection with Brucella Species?

Answer 33

Undulating fever - high during day and low during night Night sweats Joint pain Anemia and Leukopenia

Question 34

How is one infected with Pasturella Multocida?

Answer 34

Cat scratch or bite, maybe dog

Question 35

Symptoms of infection with Pasturella Multocida?

Answer 35

Localized wound infection - cellulitis

Question 36

Cat scratch disease bacteria?

Answer 36

Bartonella Species

Question 37

Bartonella Species causes?

Answer 37

Cat scratch disease

Question 38

Symptoms of Bartonella Species infection?

Answer 38

Fever, malaise, lymphadenopathy Red nodules Angiomatosis

Question 39

Angiomatosis

Answer 39

- Seen with Bartonella Species infection | = Vascular proliferation