Gram (-) Bacteria - Enterics Flashcards

(40 cards)

1
Q

What enteric is a lactose fermenter and a normal part of the GI flora?

A

Escherichia Coli (E. Coli)

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2
Q

What does Escherichia Coli have that allows it to adhere to host cells?

A

Pili

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3
Q

Overall, what 4 diseases does Escherichia Coli cause?

A

Diarrhea
UTI
Neonatal Meningitis
Pneumonia

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4
Q

1 cause of a UTI?

A

Escherichia Coli

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5
Q

3 specific strains of Escherichia Coli that can cause diarrheal illnesses?

A

ETEC
EIEC
EHEC

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6
Q

What toxins are associated with ETEC strain of Escherichia Coli?

A

Heat labile and Heat stabile toxins

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7
Q

What type of diarrhea does the ETEC strain of Escherichia Coli cause?

A

Watery diarrhea

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8
Q

EIEC strain of Escherichia Coli contains?

A

Invasive plasmid

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9
Q

What type of diarrhea does the EIEC strain of Escherichia Coli cause?

A

Bloody diarrhea

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10
Q

What toxin is associated with the EHEC strain of Escherichia Coli?

A

Shiga - like toxin 1 and 2

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11
Q

What type of diarrhea does the EHEC strain of Escherichia Coli cause?

A

Bloody diarrhea

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12
Q

ETEC, EIEC, EHEC diarrhea types

A

ETEC - watery

EIEC, EHEC - bloody

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13
Q

What strain of Escherichia Coli is Hemolytic Uremic Syndrome (HUS) caused by?

A

EHEC 0157

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14
Q

Symptoms of Hemolytic Uremic Syndrome (HUS) due to EHEC?

A

Anemia
Thrombocytopenia
Renal failure

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15
Q

Shigella is what shape?

A

Rod

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16
Q

Most common shigella in the U.S?

A

S. Sonnei

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17
Q

What is the toxin produced with shigella?

18
Q

Action of Shiga toxin?

A

Inhibits 60S ribosomal subunit and thus, protein synthesis = cell death

19
Q

Inhibits 60S ribosomal subunit and thus, protein synthesis = cell death

20
Q

What strain of shigella produces shiga toxin?

A

S. Dysenteriae

21
Q

Symptoms with Shigella infection?

A

Fever and bloody diarrhea

22
Q

Salmonella Typhi causes?

A

Typhoid Fever

23
Q

What causes Typhoid fever?

A

Salmonella Typhi

24
Q

“Typhoid Mary”

A

ASYMPTOMATIC carrier of Salmonella Typhi

25
Symptoms of Typhoid Fever due to salmonella typhi?
Stepwise fever - rises during day and drops in morning RUQ pain and rose spots on abdomen Delirium when fever peaks Gallbladder issues
26
What type of salmonella is found in virtually all animals?
Non-typhoidal salmonella
27
Symptoms of infection due to non-typhoidal salmonella?
Gastroenteritis and 1/2 will get a fever
28
Symptoms of Typhoid Fever due to salmonella typhi?
Stepwise fever - rises during day and drops in morning RUQ pain and rose spots on abdomen Delirium when fever peaks Gallbladder issues
29
What is a common source of Yersinia Enterocolitica?
Milk products
30
Symptoms of infection with Yersinia Enterocolitica?
Pseudoappendicitis, fever, diarrhea
31
What bacteria commonly mimics appendicitis?
Yersinia Enterocolitica
32
What bacteria has a swarming growth pattern of concentric rings?
Proteus Mirabilis
33
Proteus Mirabilis growth pattern?
Swarming concentric rings
34
Proteus Mirabilis is ____ (+)
Urease (+)
35
Job of urease?
Breaks down urea into CO2 and ammonia
36
What color will the urine turn in the lab with urease (+)
Pink
37
Proteus Mirabilis is a common cause of?
UTI in nosocomial setting
38
What population is at higher risk for infection with Klebsiella Pneumoniae?
Alcoholics and Hospitalized patients
39
Symptoms of Klebsiella Pneumoniae?
Necrotizing pneumonia with currant jelly sputum
40
What type of disease is associated with Klebsiella Pneumoniae?
Necrotizing pneumonia with currant JELLY sputum