DNA Virus - Herpesvirus

Question 1

A virus is an infectious agent that contain?

Answer 1

Either DNA or RNA

Question 2

Viruses require what type of cells?

Answer 2

Living cells for energy

Question 3

Viruses - intracellular or extracellular?

Answer 3

Intracellular

Question 4

How big are viruses?

Answer 4

TINY

Question 5

What are the DNA Viruses?

Answer 5

HHAPPPy

• Herpesvirus
• Hepadnavirus
• Adenovirus
• Papovavirus
• Parvovirus
• Poxvirus

Question 6

What are the DNA Viruses?

Answer 6

HHAPPPy

• Herpesvirus
• Hepadnavirus
• Adenovirus
• Papovavirus
• Parvovirus
• Poxvirus

Question 7

What are the DNA Viruses?

Answer 7

HHAPPPy

• Herpesvirus
• Hepadnavirus
• Adenovirus
• Papovavirus
• Parvovirus
• Poxvirus

Question 8

What are the main Herpesviruses?

Answer 8

Herpes Simplex Viruses 1 and 2
Varicella - Zoster Virus
Epstein - Barr Virus
Cytomegalovirus
Roseola (HHV-6)
HHV-8

Question 9

How are Herpes Simplex Viruses 1 and 2 spread?

Answer 9

Skin-to-skin contact

Question 10

Herpes Simplex Virus (HSV) 1 involves what part of the body?

Answer 10

Orofacial

Question 11

Herpes Simplex Virus (HSV) 2 involves what part of the body?

Answer 11

Genital

Question 12

What are common orofacial and finger infections seen with Herpes Simplex Virus?

Answer 12

Gingivostomatitis (orofacial involvement)
Herpetic Whitlow (finger infection)

Question 13

Herpes Simplex Viruses 1 and 2 are causes of neonatal infection/death and are a part of the?

Answer 13

TORCH

Question 14

What is the number 1 cause of encephalitis (inflammation of the brain)?

Answer 14

Herpes Simplex Virus

Question 15

2 diseases caused by the Varicella-Zoster Virus?

Answer 15

Chickenpox (Varicella)

Shingles (Herpes Zoster)

Question 16

The Varicella portion of the Varicella-Zoster Virus affects who how?

Answer 16

Children

- Aerosolized transmission and skin-to-skin transmission

Question 17

How long is the incubation period for the Varicella portion of the Varicella-Zoster Virus?

Answer 17

2 weeks

Question 18

Symptoms of Chickenpox (Varicella)?

Answer 18

Rash: Papules -> Vesicles -> Scabs

Fever, malaise

Question 19

How does one get Shingles (Herpes Zoster)?

Answer 19

Reactivation of latent infection in the DRG

Question 20

Symptoms of Shingles (Herpes Zoster)?

Answer 20

Painful, burning lesion in dermatomal distribution

Question 21

What determines where the lesion will be with Shingles (Herpes Zoster)?

Answer 21

Dermatome!

Question 22

How is Epstein-Barr Virus spread?

Answer 22

Saliva, toothbrushes, kissing, utensils

Question 23

What population and cells does the Epstein - Barr Virus affect?

Answer 23

Young adults

- AFFECTS B CELLS

Question 24

Via ____ receptor, Epstein - Barr virus affects B cells directly

Answer 24

C3d

Question 25

What does the Epstein - Barr virus cause and what are the symptoms?

Answer 25

Sore throat Fever Lymphadenopathy Hepatosplenomegaly

Question 26

What cancers are those with the Epstein - Barr virus at risk for?

Answer 26

B cell lymphomas | Nasopharyngeal carcinomas

Question 27

How do lymphocytes look with Epstein - Barr virus?

Answer 27

Atypical - MORE cytoplasm

Question 28

What tests and when do you do them for the Epstein - Barr virus?

Answer 28

Heterophile Ab test (monospot) -- IF NEGATIVE -- EBV Ab test

Question 29

With Cytomegalovirus, most are?

Answer 29

Asymptomatic

Question 30

CMV Mononucleosis

Answer 30

Symptoms similar to EBV mononucleosis + GREATER FEVER!!! | - caused by cytomegalovirus

Question 31

What is caused in the immunocompromised if cytomegalovirus is reactivated?

Answer 31

Chorioretinitis | = Blurry vision and floaters

Question 32

Cytomegalovirus is a ____ disease because it causes congenital intellectual disability

Answer 32

TORCH

Question 33

HHV - 6

Answer 33

Roseola

Question 34

In what age group and what are the symptoms of Roseola (HHV-6)?

Answer 34

In children | = 3-5 days of high fever -> resolves -> RASH

Question 35

3-5 days of high fever -> resolves -> RASH

Answer 35

Roseola (HHV-6)

Question 36

What does HHV-8 cause?

Answer 36

Kaposi - Sarcoma | = vascular tumor

Question 37

Symptoms of Kaposi - Sarcoma?

Answer 37

Red/purple skin nodules | -- caused by HHV-8

Question 38

In what populations is Kaposi - Sarcoma common?

Answer 38

- Caused by HHV - 8 | = Males with AIDS, in middle east and Africa