Flashcards in RNA viruses Deck (39):
What are the reoviruses and their structures?
What is Coltivirus?
Colorado Tick Fever
acute flu illness
What is rotavirus?
#1 cause of fatal diarrhea in children
increases in winter months in day care centers
What are the picornaviruses and their structure?
What happens w/ polio?
damage to the anterior motor horns
motor neurons are damaged in the pons and medulla
What's the deal with echovirus?
**get outbreaks in the summer months
What are the 2 causes of the common cold?
What's the deal with the coxsackie virus?
hand foot and mouth disease
Which of the picornaviruses are enteroviruses?
What is the structure/function of the hepevirus?
What's the deal with the caliciviruses?
**Taking a cruise off the coast of California
What is the structure of flaviviruses?
HY DSW shoes
St. Louis Encephalitis
West Nile Virus
What's the deal with yellow fever?
monkey or human reservoir
Fever, black vomit (coffee ground emesis)
Hemorrhagic disease-purpura, petechiae, epistaxis
Histo: councilman bodies (eosinophilic apoptotic globules) in liver
What is the deal with dengue?
Break bone fever--muscle/joint pain
Tourniquet test--see petechiae when you leave the BP cuff on
What are the arboviruses that can cause encephalitis?
St. Louis encephalitis-flavivirus
Eastern Equine Encephalitis-toga virus
Western Equine Encephalitis-toga
What is the structure of toga viruses? What are they?
Eastern Equine Encephalitis
Western Equine Encephaliits
What's the deal with rubella?
Congenital Rubella Syndrome (toRch)
What are the features of congenital rubella syndrome?
cardiac defects: patent ductus arteriosus, pulmonic stenosis
What are the retroviruses?
SSRNA linear, 2 copies
HTLV-T cell leukemia
**have reverse transcriptase
What are the features of the orthomyxo viruses?
SS neg. linear
What are the 2 important components of the influenza virus?
What is the risk of the influenza virus?
Who should get it?
hemagglutinin--promotes viral entry
neuraminidase--promotes release of viral progeny
**could get super infections w/ S. aureus, S. pneumo, H. influenza pneumonias
>6 mo you should have it!
What is the makeup of the vaccine for flu?
Trivalent: 2A, 1 B
Quadrivalent: 2A, 2B
**can get intranasal LAV if you are>2yo and less than 50 yo and not sick or pregnant
What are the features of the paramyxoviruses?
SS neg. strand linear
What are the features of croup?
caused by parainfluenza virus
seal-like barking cough
steeple sign on X-ray
**severe: pulsus paradoxus
Treatment: epi, dexamethasone, O2
What are the important features of RSV?
bronchiolitis and pneumonia
brassy cough, expiratory wheezing, resp distress
seen in winter months
F fusion protein fuses w/ other cells and get a giant syncytium
What is the treatment sometimes used for RSV?
but mainly supportive
Which conditions are caught during the winter months? Summer months?
Enteroviruses, coxsackie, polio
What is ribavirin and what does it help with?
guanosine analog drug
competitively inhibits IMP dehydrogenase
helps w/ Hep C and RSV
SE: teratogen, hemolytic anemia
What are the 2 drugs to treat Hep C?
What are the important features of measles?
maculopapular rash head-->feet
Vit A may help
What are the important features of mumps?
Mumps uses POM POMS
What are the rhabdoviruses?
SS neg. linear RNA
What are the important features of rabies?
negri bodies on histo
Fever, malaise N/V-->agitation, photophobia, hydrophobia, hallucinations, hypersalivation-->paralysis, coma, death
**travels up peripheral nerves to CNS via retrograde transport
What are the important features of the filoviruses?
encapsulated single stranded neg. RNA
What are the important features of Ebola virus?
targets endothelial cells, phagocytes, hepatocytes
begins with fever, myalgia
diffuse hemorrhage, DIC, shock
*transmission via direct contact w/ bodily fluids
Which viruses and bacteria can you contract from animal urine?
What are the important features of the hantavirus?
pulmonary syndrome: fever, pulmonary edema, resp failure
spread by aerosolized mouse urine
What are the important features of H1N1?
flu + GI symptoms
give oseltamivir or zanamivir