2.5.3 Assessment of Liver Function (Bilirubin Metabolism) Flashcards

1
Q

Bilirubin (B1) is first transported in the portal system, bound mainly to?

a. Albumin
b. Urobilinogen
c. Iron
d.RBC

A

a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Upon entering the hepatocyte, B1 is transported to ___________ where it is conjugated in the presence of the enzyme?

a. Rougn ER, UDPGT
b. Smooth ER, UDPGT
c. Rough ER, UPDGT
d. Smooth ER, UPDGT

A

b

uridyl diphosphoglucuronyl transferase (UDPGT)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Conjugated bilirubin (B2) is then ___________ to bile canaliculi and _________ to the intestinal tract

A

Secreted

Excreted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

B2 is further metabolized in the small intestine by the bacteria into _________

A

Urobilinogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Majority of urobilinogen is reabsorbed and re-excreted by the liver so the minor fraction is excreted in the __________

A

Urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The intestinal urobilinogen in converted into stool pigment called?

A

Urobilin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly