1.1.6 Basic Principles and Techniques (Quality Assurance: Lab testing process, QC)

Question 1

Quality Management, Quality Assurance, Quality Control

Is this the hierarchy of order?
T or F

Answer 1

T

Question 2

Include test requisition, patient preparation, patient identification, specimen collection, labelling, specimen transport, specimen reception, handling, and preparation

a. Pre-analytical
b. Analytical
c. Post-analytical

Answer 2

a

More on Samples and patient related

Question 3

One of the essential aspects in the Analytical phase?

Answer 3

Quality control (Controls)

Question 4

Include reagents, preventive maintenance of equipment, calibration, analysis of samples, and QUALITY CONTROL

a. Pre-analytical
b. Analytical
c. Post-analytical

Answer 4

b

More focus on lab equipment and controls

Question 5

Include verification of calculations and reference ranges, flagging and notification of panic/critical values, delta checks, and reporting of results

a. Pre-analytical
b. Analytical
c. Post-analytical

Answer 5

c

Question 6

An algorithm in which a current laboratory result is compared with results obtained on a previous specimen from the same patient

Answer 6

Delta check

Question 7

Delta checks detect _______ and ________ errors

Answer 7

Pre-analytical and analytical

Question 8

Closeness of the result to the true or actual value

a. Reliability
b. Accuracy
c. Precision

Answer 8

b

Question 9

Ability to produce a series of results that agree closely with each other

a. Reliability
b. Accuracy
c. Precision

Answer 9

c

Question 10

Ability to maintain ACCURACY and PRECISION over an extended period of time during which equipment, reagents, and personnel may change

a. Reliability
b. Accuracy
c. Precision

Answer 10

a

Question 11

Precision is also known as?

Answer 11

Repeatability or reproducibility

Question 12

Commonly expressed in terms of coefficient of variation

a. Reliability
b. Accuracy
c. Precision

Answer 12

c

Question 13

Repeatability means within-run precision

Reproduciblity means in between run or interlab precision

T or F

Answer 13

T

Repeatability indicates repeating series of same or almost same result with the same equipment

Reproducibility indicates regardless of personnel or equipment or places as long as it can reproduce the same result

Question 14

Internal QC Involves the analysis at Least _____ of control every ________

Answer 14

2

24 hrs

Question 15

In Internal QC, Initial control limits are established by analyqing control materials for at least ____ consecutive days or runs

Answer 15

20

Question 16

Important for the daily monitoring of accuracy and precision of analytical methods

a. Internal QC
b. External QC

Answer 16

a

Question 17

Involves testing blind samples (unknown concentration of analytes) sent periodically by regulatory agencies to participating laboratories

a. Internal QC
b. External QC

Answer 17

b

Question 18

Important for maintaining the long-term accuracy of analytical methods

a. Internal QC
b. External QC

Answer 18

b

Question 19

What is the Reference Laboratory for clinical chemistry?

Answer 19

Lung Center of the Philippines

Question 20

Standard Deviation Index (SDI) is also known as?

Answer 20

z score

Question 21

Proficiency testing

a. Internal QC
b. External QC

Answer 21

b

Question 22

SDI greater than 2 is a poor performance

T or F

Answer 22

T

Question 23

Formula for SDI?

Answer 23

SDI = (lab result - mean) / standard deviation