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MTAP 1 Clinical Chemistry > 2.2.2 Lipids and Lipoproteins (Major classes of lipoproteins)) > Flashcards

2.2.2 Lipids and Lipoproteins (Major classes of lipoproteins)) Flashcards

1
Q

Density:

<0.93

a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL

A

a

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2
Q

Density:

0.93-1.006

a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL

A

b

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3
Q

Density:

1.006-1.019

a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL

A

e

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4
Q

Density:

1.019-1.063

a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL

A

c

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5
Q

Density:

1.062 - 1.21

a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL

A

d

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6
Q

Electrophoretic mobility:

Pre-beta

a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL

A

b

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7
Q

Electrophoretic mobility:

Alpha

a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL

A

d

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8
Q

Electrophoretic mobility:

Beta

a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL

A

c

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9
Q

Electrophoretic mobility:

origin

a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL

A

a

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10
Q

Major Component:

Cholesterol

a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL

A

c

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11
Q

Major Component:

Protein 50%

a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL

A

d

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12
Q

Major Component:

Tryglyerides (Endogenous

a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL

A

b

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13
Q

Major Component:

Triglycerides (Exogenous)

a. Chylomicron
b. VLDL
c. LDL
d. HDL
e. IDL

A

a

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14
Q

Apolipoproteins:

B48, C, E

a. Chylomicron
b. VLDL
c. LDL
d. HDL

A

a

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15
Q

Apolipoproteins:

B100, C, E

a. Chylomicron
b. VLDL
c. LDL
d. HDL

A

b

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16
Q

Apolipoproteins:

B100

a. Chylomicron
b. VLDL
c. LDL
d. HDL

A

c

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17
Q

Apolipoproteins:

AI, AII, C, E

a. Chylomicron
b. VLDL
c. LDL
d. HDL

A

d

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18
Q

Comments:

Transports endogenous triglycerides

a. Chylomicron
b. VLDL
c. LDL
d. HDL

A

b

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19
Q

Comments:

Transports Exogenous triglycerides

a. Chylomicron
b. VLDL
c. LDL
d. HDL

A

a

20
Q

Comments:

Transports cholesterol to peripheral tissues

a. Chylomicron
b. VLDL
c. LDL
d. HDL

A

c

21
Q

Comments:

Facilitates reverse cholesterol transports (From th tissues back to the liver)

a. Chylomicron
b. VLDL
c. LDL
d. HDL

A

d

22
Q

Gold standard for lipoprotein analysis?

A

Ultracentrifugation / Density gradient centrifugation

23
Q

2 important methods for lipoprotein analysis?

A

Ultracentrifugation and electrophoresis

24
Q

Chylomicron has lower density than the water

T or F

A

T

25
Q

IDL is considered Major lipoprotein

T or F

A

F

Minor

26
Q

Arrangement of lipoproteins from least dense to most dense?

A

Chylomicrons>VLDL>LDL>HDL

27
Q

Lipoproteins travels from Cathode (-) to Anode (+)

T or F

A

T

28
Q

Arrangement of lipoproteins in terms of mobility in electrophoresis from CATHODE (-) TO ANODE (+):

A

Chylomicrons>LDL>VLDL>HDL

29
Q

The most Triglyceride rich

a. Chylomicron
b. VLDL
c. LDL
d. HDL

A

a

30
Q

The triglyceride transported by chylomicrons is dietary (Exogenous)

T or F

A

T

31
Q

The triglyceride carried by VLDL is synthesized by the ?

A

Liver

32
Q

Main determinant of cholesterol level?

A

LDL

33
Q

Known as atherogenic or may promote atherosclerosis

A

LDL

34
Q

most protein-rich lipoprotein

A

HDL

35
Q

A lipoprotein that serves as a scavenger that can remove
cholesterol excess deposits.

A

HDL

36
Q

HDL deliver Cholesterol back to the liver so it can be use to synthesize ?

A

Bile

37
Q

Important in the saponification of digestion of dietary lipids in the intestine.

A

Bile

38
Q

chylomicrons are not taken up by the liver because of its huge size

T or F

A

T

39
Q

Chylomicrons needs to be hydrolyze into remnants so it can be taken up by the liver

T or F

A

T

40
Q

Enzyme catalyze the hydrolysis of chylomicrons, IDL, and VLDL

a. Protein Lipase
b. Lipoprotein lipase
c. Lipidolipase
d. Lipase

A

b

41
Q

Liver synthesizes the chylomicrons remnants into?

A

VLDL

42
Q

VLDL is hydrlyzes into smaller particle which is?

A

IDL

43
Q

IDL is also hydrolyzes in to much smaller particle which is?

A

LDL

This can be easily taken up by the cell

44
Q

LDL is a metabolite of VLDL

T or F

A

T

45
Q

Function of cholesterol in the body includes:

  • Synthesis of Steroid hormone
  • Synthesis of Vit D
  • Synthesis of Bile

Which of the following does not belong?

A

None

46
Q

Why does VLDL migrate faster in electrophoresis?

A

It has higher magnitude of NEGATIVE charge

47
Q

What is the major lipid component (Excluding the protein) of the HDL?

a. Triglyceride
b. Phospholipids
c. Fatty acids

A

Phopholipids

MTAP 1 Clinical Chemistry (97 decks)

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