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MTAP 1 Clinical Chemistry > 2.4.3 Proteins (Serum protein Fractions) > Flashcards

2.4.3 Proteins (Serum protein Fractions) Flashcards

(47 cards)

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1
Q

Indicator of malnutrition

a. Pre albumin
b. Albumin

A

a

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2
Q

Major contributor to plasma oncotic/osmotic pressure

a. Pre albumin
b. Albumin

A

b

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3
Q

Binds/Transport T4 as Transthyretin/TBPA

a. Pre albumin
b. Albumin

A

a

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4
Q

Forms a complex with retinol Binding protein (RBP)

a. Pre albumin
b. Albumin

A

a

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5
Q

Second most abundant protein fraction in CSF

a. Pre albumin
b. Albumin

A

a

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6
Q

General transport protein

a. Pre albumin
b. Albumin

A

b

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7
Q

Decrease levels in Nephrotic syndrome, protein-losing enteropathy and liver disease

a. Pre albumin
b. Albumin
c. Haptoglobulin
d. Transferrin

A

b

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8
Q

Most abundant fraction

a. Pre albumin
b. Albumin

A

b

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9
Q

This is not distinct in Serum electrophoresis

a. Pre albumin
b. Albumin
c. Immunoglobulin
d. CRP

A

a

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10
Q

Absence of albumin

a. Analbuminemia
b. bisalbuminemia

A

a

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11
Q

Albumin

Negative APR: Decrease in_______________

a. Transport of substance
b. Inflammation
c. Analytes
d. None of the above

A

b

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12
Q

The following are Alpha 1 protein except:

  • 𝜢-Fetroprotein
  • 𝜢1- Antitrypsin
  • 𝜢1- Acid glycoprotein
  • 𝜢1-Antichymotrypsin
  • Gc-globulin
  • Haptoglobulin
A

Haptoglobulin ( 𝜢2)

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13
Q

Increase levels in amniotic fluid NEURAL TUBE DEFECT

a. 𝜢-Fetroprotein
b. 𝜢1- Antitrypsin
c. 𝜢1- Acid glycoprotein
d. 𝜢1-Antichymotrypsin
e. Gc-globulin

A

a

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14
Q

Acute Phase Reactant

a. 𝜢-Fetroprotein
b. 𝜢1- Antitrypsin
c. 𝜢1- Acid glycoprotein
d. 𝜢1-Antichymotrypsin
e. Gc-globulin

A

b and c

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15
Q

Transport Vit D

a. 𝜢-Fetroprotein
b. 𝜢1- Antitrypsin
c. 𝜢1- Acid glycoprotein
d. 𝜢1-Antichymotrypsin
e. Gc-globulin

A

e

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16
Q

Protease inhibitor

a. 𝜢-Fetroprotein
b. 𝜢1- Antitrypsin
c. 𝜢1- Acid glycoprotein
d. 𝜢1-Antichymotrypsin
e. Gc-globulin

A

b and d

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17
Q

Binds progesterone and some drugs

a. 𝜢-Fetroprotein
b. 𝜢1- Antitrypsin
c. 𝜢1- Acid glycoprotein
d. 𝜢1-Antichymotrypsin
e. Gc-globulin

A

c

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18
Q

Major component for alpha 1 region?

a. 𝜢-Fetroprotein
b. 𝜢1- Antitrypsin
c. 𝜢1- Acid glycoprotein
d. 𝜢1-Antichymotrypsin
e. Gc-globulin

A

b

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19
Q

Increase level in adult serum which may cause Hepatocellular CA/Liver cancer

a. 𝜢-Fetroprotein
b. 𝜢1- Antitrypsin
c. 𝜢1- Acid glycoprotein
d. 𝜢1-Antichymotrypsin
e. Gc-globulin

20
Q

Deficiency is associated with SERPINA 1 gene mutation and causes juvenile hepatic cirrhosis and pulmonary emphysema

a. 𝜢-Fetroprotein
b. 𝜢1- Antitrypsin
c. 𝜢1- Acid glycoprotein
d. 𝜢1-Antichymotrypsin
e. Gc-globulin

21
Q

Binds prostate specific antigen

a. 𝜢-Fetroprotein
b. 𝜢1- Antitrypsin
c. 𝜢1- Acid glycoprotein
d. 𝜢1-Antichymotrypsin
e. Gc-globulin

22
Q

Decrease level may lead to abnormal calcium level

a. 𝜢-Fetroprotein
b. 𝜢1- Antitrypsin
c. 𝜢1- Acid glycoprotein
d. 𝜢1-Antichymotrypsin
e. Gc-globulin

23
Q

Negatively charged even in in pH, has a very high CHO content

a. 𝜢-Fetroprotein
b. 𝜢1- Antitrypsin
c. 𝜢1- Acid glycoprotein
d. 𝜢1-Antichymotrypsin
e. Gc-globulin

24
Q

The following are Alpha 2 protein except:

  • 𝜢2-Macroglobulin
  • Hepatoglobulin
  • Ceruplasmin
  • Transferrin
  • Hemopexin
Study These Flashcards
A

Transferrin and Hemopexin

25
A Protease inhibitor and the largest non-Ig protein a. 𝜢2-Macroglobulin b. Hepatoglobulin c. Ceruloplasmin
a
26
The following are PROTEASE INHIBITOR except: - 𝜢2-Macroglobulin - 𝜢1-Antitrypsin - 𝜢1- antichymotrypisin - 𝜢1- Acid glycoprotein
- 𝜢1- Acid glycoprotein
27
An acute Phase reactant that BINDS to hemoglobin to PRESERVE IRON a. 𝜢2-Macroglobulin b. Hepatoglobulin c. Ceruloplasmin
b
28
An acute phase reactant that is a binding protein and has oxidase activity a. 𝜢2-Macroglobulin b. Hepatoglobulin c. Ceruloplasmin
c
29
Increase ten-fold in Nephrotic syndrome and protein-losing enteropathy a. 𝜢2-Macroglobulin b. Hepatoglobulin c. Ceruloplasmin
a same with albumin but decrease
30
Decrease level seen in hemolytic disorders/Intravascular hemolysis a. 𝜢2-Macroglobulin b. Hepatoglobulin c. Ceruloplasmin
b
31
Decrease level seen in Wilson's disease a. 𝜢2-Macroglobulin b. Hepatoglobulin c. Ceruloplasmin
c
32
The following are acute phase reactant except: - Haptoglobulin - Ceruloplasmin - 𝜢𝟏- Antitrypsin - 𝜢𝟏 - Acid glycoprotein
None
33
Serve as both APR and protease inhibitor a. Haptoglobulin b. Ceruloplasmin c. 𝜢𝟏- Antitrypsin d. 𝜢𝟏 - Acid glycoprotein
c
34
The following are beta globulins except: - Transferrin - C3 complement - Hemopexiin - Ξ’2-microglobulin - CRP
CRP
35
Immune response a. Transferrin b. C3 complement c. Hemopexiin d. Ξ’2-microglobulin
b
36
Transports iron a. Transferrin b. C3 complement c. Hemopexiin d. Ξ’2-microglobulin
a
37
What is the difference between transferrin and haptoglobin?
Haptoglobulin: Preserves iron Transferrin: Transport iron
38
Binds heme a. Transferrin b. C3 complement c. Hemopexiin d. Ξ’2-microglobulin
c
39
Component of MHC or HLA molecules a. Transferrin b. C3 complement c. Hemopexiin d. Ξ’2-microglobulin
d
40
Increase level seen in Iron deficiency anemia a. Transferrin b. C3 complement c. Hemopexiin d. Ξ’2-microglobulin
a
41
Mos abundant complement component?
C3 complement
42
Decrease level in intavascular hemolysis a. Transferrin b. C3 complement c. Hemopexiin d. Ξ’2-microglobulin
c
43
Use to measure GFR a. Transferrin b. C3 complement c. Hemopexiin d. Ξ’2-microglobulin
d
44
The followin are gamma protein except: - C-reactive protein - IgG - IgM - Immunoglobulins
None
45
Increased up to 1000 times i inflammatory states; hs CRP used as marker for cardiovascular disorder a. C-reactive protein b. Immunoglobulins
a
46
Immunoglobulins are produced by what cell?
Plasma cell/Memory cell/B cell
47
Extra bands is seen if specimen is: Plasma = __________ - Forms a band between beta and _______ region Hemolyzed = Hemoglobin - Forms a band between alpha 2 and beta
Fibrinogen - gamma region

MTAP 1 Clinical Chemistry (97 decks)

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