2.5.3 Assessment of Liver Function (Bilirubin Metabolism)

Question 1

Bilirubin (B1) is first transported in the portal system, bound mainly to?

a. Albumin
b. Urobilinogen
c. Iron
d.RBC

Answer 1

a

Question 2

Upon entering the hepatocyte, B1 is transported to ___________ where it is conjugated in the presence of the enzyme?

a. Rougn ER, UDPGT
b. Smooth ER, UDPGT
c. Rough ER, UPDGT
d. Smooth ER, UPDGT

Answer 2

b

uridyl diphosphoglucuronyl transferase (UDPGT)

Question 3

Conjugated bilirubin (B2) is then ___________ to bile canaliculi and _________ to the intestinal tract

Answer 3

Secreted

Excreted

Question 4

B2 is further metabolized in the small intestine by the bacteria into _________

Answer 4

Urobilinogen

Question 5

Majority of urobilinogen is reabsorbed and re-excreted by the liver so the minor fraction is excreted in the __________

Answer 5

Urine

Question 6

The intestinal urobilinogen in converted into stool pigment called?

Answer 6

Urobilin