2.3.1 Nonprotein Nitrogen Compounds (Urea) Flashcards

1
Q

Urea is the Lowest concentration in the blood

T or F

A

F

Highest

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2
Q

Urea comprises of __________ of NPN mass in plasma

a. 45 - 50%
b. 50 - 55%
c. 40 - 45%
d. 35 - 40%

A

a

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3
Q

Urea is formed in the ______ from CO2 and ammonia

A

liver

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4
Q

Urea is not associated with the detoxification function of the liver

T or F

A

F

Associated

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5
Q

Urea is a non toxic form of ammonia

T or F

A

T

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6
Q

Major excretory product of protein metabolism and other nitrogen-containing chemicals.

A

Urea

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7
Q

Convert BUN to urea (Formula)

A

BUN x 2.14

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8
Q

Reference method for Urea

A

IDMs

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9
Q

Chemical Method for Urea?

a. Jaffe method
b. Phophotungstic Acid method
c. Fearon Method

A

c

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10
Q

Product for Fearon method when Diacetyl combine with urea?

a. Diacetyl monoxime
b. Formazan
c. Diazine

A

c

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11
Q

Color of diazine?

A

Yellow

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12
Q

Enzymatic method for urea:

Colorimetric:
- Nesselrization
- Berthelot

T or F

A

T

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13
Q

Enzymatic method for urea:

GLDH-Couple enzymatic

T or F

A

T

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14
Q

Enzymatic method for urea:

Conductimetric is a measurement of the increase in conductivity due to the ___ and CO3^2- ions

a. Urea
b. NH4
c. Uric acid

A

NH4 (Ammonia)

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15
Q

Berthelot reaction in enzymatic method for urea, the indophenol is color?

A

Blue

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16
Q

Enzymatic method for Urea:

Glutamate dehydrogenase coupled because the initial reaction is
catalyze by _______

a. Urease
b. Lipase
c. Dehydrogenase
d. Bromase

A

a

17
Q

What is the end product for Nesslerization?

a. Indophenol
b. NAD
c. Ammonia and Carbon monoxide
d. Dimercuric ammonium iodide

A

d

18
Q

In Nesslerization, the dimercuric ammonium iodide is what color?

A

Yellow

19
Q

Enzymatic method for Urea:

If H is the end (NADH) High
absorbance

if D is the end (NAD) decrease absorbance at 340nm

T or F

A

T

20
Q

Reference interval for urea

a. 6-20 mg/dl
b. 5-15 mg/dl
c. 7-25 mg/dl
d. 8-20 mg/dl

A

a

21
Q

Azotemia:

BUN: Elevated
Creatinine: Normal

Low blood volume, dehydrated, high protein diet, increase protein catabolism

a. Prerenal
b. Renal
c. Postrenal

A

a

22
Q

Azotemia:

BUN: Elevated
Creatinine: Elevated
Excretion: Decrease

Glomerulonephritis and renal failure

a. Prerenal
b. Renal
c. Postrenal

A

b

23
Q

Azotemia:

BUN: Elevated
Creatinine: Elevated
Excretion: Decrease

Urinary tract obstruction of stone and tumors

Nephrolithiasis, tumors, severe infection

a. Prerenal
b. Renal
c. Postrenal

A

c

24
Q

Uremia/Uremic syndrome is always characterized by ___________ of BUN and creatinine.

A

elevations

25
Q

Uremia is associated with renal failure and very high plasma urea concentration

T or F

A

T