4.4.1 Toxicology Flashcards
it is the highest point which corresponds at point at which the amount of drug is distributed is greater than the amount metabolized and excreted
a. Peak
b. Trough
c. Half-life
d. Steady state
a
it is the lowest concentration achieved just before the next dose
a. Peak
b. Trough
c. Half-life
d. Steady state
b
It is the time required for the concentration of the drug decrease by half
a. Peak
b. Trough
c. Half-life
d. Steady state
c
Important in multiple dose regimen
a. Peak
b. Trough
c. Half-life
d. Steady state
c
Amount of the drug absorbed and distributed equals amount metabolized and excreted
a. Peak
b. Trough
c. Half-life
d. Steady state
d
it is where the peak and trough monitoring starting once the Steady state achieved
a. Peak
b. Trough
c. Half-life
d. Steady state
d
Range or values between the MEC and MTC that produces therapeutic effect
a. Therapeutic range
b. Minimum Effective Concentration
c. Minimum toxic concentration
a
Lowest concentration of drug in the blood the will produce ADVERSE response
a. Therapeutic range
b. Minimum Effective Concentration
c. Minimum toxic concentration
c
Lowest concentration of drug in the blood the will produce DESIRED effect
a. Therapeutic range
b. Minimum Effective Concentration
c. Minimum toxic concentration
b
Drug dose that produces BENEFICIAL effect in 50% of the population
a. TD50
b. ED50
c. Therapeutic index
b
Drug dose that produces ADVERSE effect in 50% of the population
a. TD50
b. ED50
c. Therapeutic index
a
Ratio between the TD50 and ED50
a. TD50
b. ED50
c. Therapeutic index
c
Basis for Drug monitoring
a. Therapeutic range
b. Therapeutic index
b
