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MTAP 1 Clinical Chemistry > 1.2.6 Blood Collection and Specimen Consideration (Preanalytical Variables) > Flashcards

1.2.6 Blood Collection and Specimen Consideration (Preanalytical Variables) Flashcards

1
Q

Age

a. Uncontrollable factors
b. Controllable factors

A

a

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2
Q

Gender

a. Uncontrollable factors
b. Controllable factors

A

a

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3
Q

Smoking

a. Uncontrollable factors
b. Controllable factors

A

b

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4
Q

Underlying condition

a. Uncontrollable factors
b. Controllable factors

A

a

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5
Q

Diurnal Variation (Increased):

Cortisol

a. AM
b. PM

A

a

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6
Q

Diurnal Variation (Increased):

Iron

a. AM
b. PM

A

a

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7
Q

What is the recommended timing of collection for cortisol?

A

8 AM and 4 PM

Detects cushing syndrome (No changes in the afternoon)

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8
Q

Iron is 30% lower in the __________

A

Afternoon

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9
Q

Diurnal Variation (Increased):

Growth hormone

a. AM
b. PM

A

b

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10
Q

Diurnal Variation (Increased):

ACTH

a. AM
b. PM

A

a

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11
Q

Diurnal Variation (Increased):

PTH

a. AM
b. PM

A

b

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12
Q

Diurnal Variation (Increased):

Aldosterone

a. AM
b. PM

A

a

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13
Q

Diurnal Variation (Increased):

ACP

a. AM
b. PM

A

b

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14
Q

Diurnal Variation (Increased):

TSH

a. AM
b. PM

A

b

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15
Q

Posture (Increase)

Alb

a. Standing
b. Supine to upright

A

a and b

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16
Q

Posture (Increase)

Cholesterol

a. Standing
b. Supine to upright

A

a

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17
Q

Posture (Increase)

Protein and bound substances

a. Standing
b. Supine to upright

A

b

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18
Q

Posture (Increase)

Calcium

a. Standing
b. Supine to upright

A

a

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19
Q

Posture (Increase)

Renin

a. Standing
b. Supine to upright

A

a

20
Q

Posture (Increase)

Aldosterone

a. Standing
b. Supine to upright

A

a

21
Q

Activity (Increased)

TP

a. Ambulatory
b. Exercise

A

a

22
Q

Activity (Increased)

Lactate

a. Ambulatory
b. Exercise

A

b

23
Q

Activity (Increased)

CK

a. Ambulatory
b. Exercise

A

a and b

24
Q

Activity (Increased)

Creatinine

a. Ambulatory
b. Exercise

A

b

25
Q

Activity (Increased)

LD, AST, Aldosterone

a. Ambulatory
b. Exercise

A

b

26
Q

Catecholamines (Ephinephrine, Nonephinephrin), Cortisol, ACTH, Aldosterone, Prolactine is increased in what factor?

A

Stress

27
Q

Diet:

Fasting Plasma glucose

a. REQUIRE fasting
b. BASAL fasting

A

a

28
Q

Diet:

OGTT (Oral glucose tolerance test)

a. REQUIRE fasting
b. BASAL fasting

A

a

29
Q

Diet:

Triglyceride, Glucose

a. REQUIRE fasting
b. BASAL fasting

A

a and b

30
Q

Diet:

Lipid profile

a. REQUIRE fasting
b. BASAL fasting

A

a

31
Q

Diet:

Insulin

a. REQUIRE fasting
b. BASAL fasting

A

a

32
Q

Diet:

Cholesterol

a. REQUIRE fasting
b. BASAL fasting

A

b

33
Q

Diet:

Electrolyte

a. REQUIRE fasting
b. BASAL fasting

A

b

34
Q

Cholesterol is Not required for fasting

T or F

A

T

Required BASAL fast

35
Q

Diet:

Gastrin

a. REQUIRE fasting
b. BASAL fasting

A

a

36
Q

Causes Increase in CO, NH3, and BUN (specifically in Urease method - False increase)

A

Smoking

37
Q

IV contamination:

Glucose

a. False increase
b. False decrease

A

a

38
Q

IV contamination:

Dilutional effect (BUN - hydration)

a. False increase
b. False decrease

A

b

39
Q

IV contamination:

Electrolytes and drug

a. False increase
b. False decrease

A

a

40
Q

Hemoconcentration causes False ____________ due to:

  • Potassium
  • Lactate
  • Protein and protein-bound substance
A

Increase

41
Q

Most greatly affected when it comes to Hemolysis (False increase)

Intracellular ions: Potassium, Magnesium, Phosphate

Which among the three is the most abundant Cation?

A

Potassium

42
Q

Most greatly affected when it comes to Hemolysis (False increase)

Intracellular ions: Potassium, Magnesium, Phosphate, iron

Which among the three is the most abundant Anion?

A

Phosphate (PO4)

43
Q

Most greatly affected when it comes to Hemolysis (False increase)

Enzymes: LD, ACP, ALP, AST, ALT, ChE

T or F

A

T

44
Q

Slight hemolysis has an significant affect on CK

T or F

A

F

Not significant

45
Q

Handling:

ABG, Ammonia, Lactate, ACTH

a. Ice/Chilling
b. Anaerobic
c. X light

A

a

46
Q

Handling:

ABG, ammonia, ACP, ionized Calcium

a. Ice/Chilling
b. Anaerobic
c. X light

A

b

47
Q

Handling:

Bilirubin, porpyrin, Carotene, Vit A and B12

a. Ice/Chilling
b. Anaerobic
c. X light

A

c

MTAP 1 Clinical Chemistry (97 decks)

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