4.2.4.2 Major Hormones (Adrenal Hormones, Lab Diag) Flashcards

1
Q
  • Urine Free Cortisol collected over 24 HOURS
  • Midnight Salivary Cortisol
  • DEXAMETHASONE Suppression Test
  • Plasma ACTH- requires use of PRE-CHILLED TUBE

a. Primary Aldosteronism
b. Cushing’s Syndrome
c. Addison’s disease (Primary hypoadrenalism)
d. Congenital adrenal hyperplasia
e. Phaeochromocytoma
f. Neuroblastoma

A

b

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q
  • ACTH stimulation (Cortrosyn) test
  • Insulin tolerance test
  • Metyrapone test: FERRIMAN GALLWEY SCROING SYSTEN or SCALE

a. Primary Aldosteronism
b. Cushing’s Syndrome
c. Addison’s disease (Primary hypoadrenalism)
d. Congenital adrenal hyperplasia
e. Phaeochromocytoma
f. Neuroblastoma

A

c

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q
  • Urine Homovanillic acid
  • Vanillylmandelic acid

a. Primary Aldosteronism
b. Cushing’s Syndrome
c. Addison’s disease (Primary hypoadrenalism)
d. Congenital adrenal hyperplasia
e. Phaeochromocytoma
f. Neuroblastoma

A

f

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q
  • Plasma Free Metanephrine / Normetanephrine
  • CLONIDINE suppression test

a. Primary Aldosteronism
b. Cushing’s Syndrome
c. Addison’s disease (Primary hypoadrenalism)
d. Congenital adrenal hyperplasia
e. Phaeochromocytoma
f. Neuroblastoma

A

e

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q
  • 21-Hydroxylase
  • Plasma 17-hydroxyprogesterone and pregnanetriol
  • Urinary Pregnanetriol
  • 17-ketosteroids
  • Scale used for grading HIRSUTISM:

a. Primary Aldosteronism
b. Cushing’s Syndrome
c. Addison’s disease (Primary hypoadrenalism)
d. Congenital adrenal hyperplasia
e. Phaeochromocytoma
f. Neuroblastoma

A

d

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q
  • Urinary Potassium excretion
  • Captopril suppression
  • Upright PA/PRA ratio
  • 18-Hydroxycorticosterone

a. Primary Aldosteronism
b. Cushing’s Syndrome
c. Addison’s disease (Primary hypoadrenalism)
d. Congenital adrenal hyperplasia
e. Phaeochromocytoma
f. Neuroblastoma

A

a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Pituitary: Cushing’s disease
Adrenal cortex: Cushing’s syndrome

T or F

A

T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Plasma cortisol: ↑
Plasma ACTH: ↓ or undetectable
HD-DST: No

a. Cushing Syndrome
b. Cushing Disease
c. Ectopic CS

A

a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Plasma cortisol: ↑
Plasma ACTH: ↑
HD-DST: Yes

a. Cushing Syndrome
b. Cushing Disease
c. Ectopic CS

A

b

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Plasma cortisol: ↑↑
Plasma ACTH: ↑↑↑
HD-DST: Usually not suppressed

a. Cushing Syndrome
b. Cushing Disease
c. Ectopic CS

A

c

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Dexamethasone does not suppress cortisol production in Cushing syndrome or primary Cushing.

T or F

A

T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

For hypersecretory, the test is suppression and for hyposecretory, the test is stimulation.

T or F

A

T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

congenital adrenal hyperplasia, the most common enzyme deficiency is the ___________

a. 21-Hydroxylase
b. 24-Hydroxylase
c. 22-Hydroxylase

A

a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

congenital adrenal hyperplasia:

When deficient, blocked synthesis of aldosterone and cortisol happens which is why there is a shift in ______________

a. Androgen secretion
b. Estrogen secretion
c. Cortisol secretion

A

a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly