4.4.1 Toxicology Flashcards

1
Q

it is the highest point which corresponds at point at which the amount of drug is distributed is greater than the amount metabolized and excreted

a. Peak
b. Trough
c. Half-life
d. Steady state

A

a

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2
Q

it is the lowest concentration achieved just before the next dose

a. Peak
b. Trough
c. Half-life
d. Steady state

A

b

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3
Q

It is the time required for the concentration of the drug decrease by half

a. Peak
b. Trough
c. Half-life
d. Steady state

A

c

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4
Q

Important in multiple dose regimen

a. Peak
b. Trough
c. Half-life
d. Steady state

A

c

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5
Q

Amount of the drug absorbed and distributed equals amount metabolized and excreted

a. Peak
b. Trough
c. Half-life
d. Steady state

A

d

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6
Q

it is where the peak and trough monitoring starting once the Steady state achieved

a. Peak
b. Trough
c. Half-life
d. Steady state

A

d

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7
Q

Range or values between the MEC and MTC that produces therapeutic effect

a. Therapeutic range
b. Minimum Effective Concentration
c. Minimum toxic concentration

A

a

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8
Q

Lowest concentration of drug in the blood the will produce ADVERSE response

a. Therapeutic range
b. Minimum Effective Concentration
c. Minimum toxic concentration

A

c

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9
Q

Lowest concentration of drug in the blood the will produce DESIRED effect

a. Therapeutic range
b. Minimum Effective Concentration
c. Minimum toxic concentration

A

b

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10
Q

Drug dose that produces BENEFICIAL effect in 50% of the population

a. TD50
b. ED50
c. Therapeutic index

A

b

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11
Q

Drug dose that produces ADVERSE effect in 50% of the population

a. TD50
b. ED50
c. Therapeutic index

A

a

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12
Q

Ratio between the TD50 and ED50
a. TD50
b. ED50
c. Therapeutic index

A

c

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13
Q

Basis for Drug monitoring

a. Therapeutic range
b. Therapeutic index

A

b

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