Chronic Inflammation Flashcards Preview

Medicine Term One > Chronic Inflammation > Flashcards

Flashcards in Chronic Inflammation Deck (11)
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1
Q

What cell types are involved in chronic inflammation

A

Macrophages
Plasma cells
Lymphocytes
Fibroblasts

2
Q

What is the outcome of chronic inflammation

A

features tissue or organ damage, (necrosis)

3
Q

What is the clinical presentations of chronic inflammation

A

Loss of function
Weight loss
Not a specific sore bit

4
Q

What are the two ways chronic inflammation appears

A

arising from acute inflammation

arising as a primary lesion

5
Q

What are the steps in granulation tissue

A

Capillaries grow into mass
Plasma proteins (platelts)
Macrophages come from blood and tissue
fibroblasts lay down collagen to repair damaged tissue
crosslinking occurs pulling skin tighter together - narrowing
forming scar

6
Q

When can fibrosis become a problem

A

Leads to chronic inflammation

Loss of functions in organs

7
Q

What is granulation an outcome of and what can it lead to

A

Acute inflammation that can lead to Chronic inflammation

8
Q

What are examples of chronic inflammation from acute inflammation

A
Acne
Cholecystitis (inflammation of the gall bladder) 
Peptic ulcer 
Osteomyelitis (abscess in the bone) 
Fracture healing
9
Q

How can chronic inflammation occur as a primary lesion

A

Due to autoimmune disease, as auto antibodies are directed against own cell tissue

10
Q

Examples of autoimmune disease chronic inflammation

A

Thyroiditis,
Rheumatoid disease
Foreign body

11
Q

What are factors that can cause primary chronic inflammatory response but not an immune response

A

material resistant to digestion
exogenous substances (eg sutures, hip replacement)
endogenous substances (eg. keratin, necrotic tissue)
granulomata inflammation

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