Important Cytokines Flashcards Preview

UWORLD Notecards > Important Cytokines > Flashcards

Flashcards in Important Cytokines Deck (13):
1

IL-1

osteoclast activator
fever and acute inflammation

2

IL-2

stimulates T cells
IL

3

IL-3

simulates bone marrow

4

IL-4

simulates IgE

5

IL-5

Stimulates IgA

6

IL-6

stimulates Acute Phase Protein

7

IL-8

chemotactic for neutrophils

8

IL-12

induces differentiation of t cells into Th1 cells
activates NK cells

9

TNF-alpha

mediates septic shock
vascular leak
WBC recruitment

10

causes cachexia in chemo patients

TNF-alpha

11

what is secreted by NK cells and T cells in response to IL-12 from macrophages

IFN-y

12

what stemmalates macrophages to kill phagocytksed pathogen and inhibit the differentiation of TH2 cells

IFN-y

13

IL-10

reduces inflammation