Important Cytokines Flashcards
(13 cards)
1
Q
IL-1
A
osteoclast activator
fever and acute inflammation
2
Q
IL-2
A
stimulates T cells
IL
3
Q
IL-3
A
simulates bone marrow
4
Q
IL-4
A
simulates IgE
5
Q
IL-5
A
Stimulates IgA
6
Q
IL-6
A
stimulates Acute Phase Protein
7
Q
IL-8
A
chemotactic for neutrophils
8
Q
IL-12
A
induces differentiation of t cells into Th1 cells
activates NK cells
9
Q
TNF-alpha
A
mediates septic shock
vascular leak
WBC recruitment
10
Q
causes cachexia in chemo patients
A
TNF-alpha
11
Q
what is secreted by NK cells and T cells in response to IL-12 from macrophages
A
IFN-y
12
Q
what stemmalates macrophages to kill phagocytksed pathogen and inhibit the differentiation of TH2 cells
A
IFN-y
13
Q
IL-10
A
reduces inflammation
