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Flashcards in Pharm Deck (58)
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1

Name some drugs that should be avoided in the elderly

Antihistamines (benydryl)
TCA's
Benzo
Sulfonylureas
Indimethicin

2

Drug of choice for the treatment of paroxysmal supra ventricular tachycardia

Adenosine

3

Action of adenosine

Slows conduction through the AV node by hyper polarizing the nodal pacemaker and conducting cells

4

Side effects of adenosine

Flushing, chest burning (bronchi spams ) and hypotension

5

Drug used for chemical cardiac stress test

Adenosine

6

Name two drugs that are metabolized by methylation

6-MC
Azathioprine

7

Name a syndrome associated with a dysfunction of glucuronyl transferase system that can lead to the toxic accumulation of some drugs because of the lack of glucuronidation

Gilbert syndrome

8

Bilirubin is metabolized by what method

Glucuronidation

9

Chest pain that occurs with activity only

Stable angina

10

Why avoid nitrates in HOCM

Because they decrease left ventricular volume which worsens left ventricular tract obstruction which worsens the situation

11

Raynuad is associated with what drugs

Amphetamines
Ergotamine
Chemo drugs

12

The ability for a drug to illicit and effect?

Efficacy

13

The dose of a drug that is needed to produce a given effect

Potency

14

Lower ED 50 means what?

A greater amount of potency

15

What does the stimulation of D1 do

Raises cAMP and causes vasodilation in most arterial beds and decreases BP

16

What is a D1 receptor short acting agonist used in severe HtN

Fenoldopam

17

A drug that causes renal vasodilation and increases naturesis. Mainly used for HTN emergency

Fenoldopam

18

Name a drug that is responsible for inhibiting GP 2b/3a from binding to fibrinogen stabilizing a platlet plug

Abciximab

19

What does Argatroban treat

Heparin induced thrombocytopenia

20

How does clopidgrel block platlet Adp receptors

By blocking P2Y12

21

Three drugs that can cause aplastic anemia

Carbamazepine
Chloramphenicol
Sulfonamides

22

Side effects of gentamicin

Vestibular and cochlear ototoxicity and nephrotoxicity

23

What happens when metronidazole is taken with alcohol

Disulfiram like reaction

24

What is used for heparin reversal

Protamine

25

At high doses what does desmopressin do

Increases factor eight activity in hemophilia a and Von willebrand disease patients

26

Drug thy treats hyperemesis gravidarum

Promethazine (antihistamine drug)

27

Antihistamine drugs that treat vomiting

Diphenhydramine
Meclizine
Promethazine

28

Dopamine receptor antagonist drugs that treat vomit

Prochlorperazine
Metoclorpramide

29

Neurokin 1 receptor antagonist that treat chemo associated vomiting

Aprepitant
Fosaprepitant

30

Five receptors associate with the area prostrema (vomiting)

M1
D2
H1
Serotonin
Neurokinin 1