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Flashcards in Random Questions Deck (68)
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1

most common cause of chronic pancreatitis

ethanol abuse

2

low HB and high MCV

macrocytic anemia

3

what is the single carbon donor that is required for the synthesis of pyrimidines and purines (thymidine) bases incorporated into DNA and without it megaloblastosis will occue

folic acid

4

why is pancreatic insufficiency associated with B12 defficiency

because B 12 needs to pancreas so that it can cleave R factor so that B12 can bind to intrinsic factor and be absorbed

5

what vitamin catalyzes the transaminase reactions by acting as a carrier of amino groups

vitamine b6 (pyridoxine)

6

what are the water shed areas in the brain

where the ACA and MCA meet and where the PCA and MCA meet

7

how do cortical watershed infarcts usually appear?

like bilateral wedge shaped strips of necrosis that are parallel and adjacent to the longitudinal issue

8

these aneurysms usually cause cerebral hemorrhage when they rupture and involve deep brain structures like the basal ganglia and thalamus, what are they called

Charcot-Bouchard Aneurysm

9

lacunar infarcts that occur in the basal ganglia, internal capsule, pons and thalamus are due to what

hypertensive arteriolar sclerosis

10

what kind of aneurysm rupture usually results in subarachnoid hemorrhage

saccular aneurysm

11

if there is alcohol abuse what will be elevated AST or ALT

AST (Think SHOTS SHOTS SHOTSS!!)

12

what is the most common cause of acute pancreatitis

gallstones

13

why is pancreatitis associated with low levels of calcium in the serum

because the pancreatitis spreads into the retroperitoneal fat, omentum and mesentery and then calcium form your system joins it and causes sopinification

14

what is the second most common cause of pancreatitis

alcohol abuse

15

what lung tumor is associated with producing ACTH or vasopressin

small cell lung cancer

16

what lung cancer is associated with producing PTHrP and hypercalcemia

squamous cell cancer of the lung

17

how to differentiate between ectopic production of ACTH like in small cell lung cancer and pituitary production of ACTH

pituitary would respond to corticosteroid administration by decreasing ACTH release due to negative feedback, while the ectopic form would not decrease with administration

18

wat is another name for small cell lung cancer

oat cell lung cancer

19

an upper motor neuron lesion will elicit what on a babinski test

dorsiflexion of the toes

20

spasticity, hyperreflecia, muscle paralysis and weakness are caused by what kind of brain lesion

upper motor neuron lesion (aka pyramidal signs)

21

lower motor neuron lesions cause what three things

muscle atrophy, muscle fasciculation and loss of tendon reflexes

22

what is the positive straight leg test

this test for sciatic nerve (l4-S3) root irritation, the patient lays supine and the leg is lifted and held straight it means that there is probably an intervertebral disc herniation causing sciatica

23

what is the triad for McCune-Albright Syndrome

1. endocrine problems (hyperthyroid)
- precocious puberty (age 7)
2. cafe-au-alit spots
3. fibrous dysplasia (osteolytic lesions that appear on the hip and pelvis bone)

24

persistant G protéine stimulation of melanocytes results in?

cafe-au-lait-macules

25

what are the first sign of McCune Albright Syndrome

cafe au last spots "Coast of Maine Border"

26

what is the main problem in McCune Albright Syndrome

mutation in the GNAS gene in embryogenesis that makes it so that G protein is ALWYAS stimulates

27

what is the lysosomal disease in A. Jews that results in diffuse painful lytic bone lesions and delayed puberty and growth

Gaucher Disease

28

what is the disease of young children that results in isolated idiopathic osteonecrosis of the hip

Legg-Calve-Perthes Disease

29

ischemic injury usually affects what part of the kidney and why t

the medulla because even under normal conditions this is the area that gets the least amount of blood

30

what are the two parts of the nephron that are susceptible to hypoxia

PCT and thick ascending limb