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Flashcards in Observational Studies Deck (11):
1

collects data from a group of people to asses the frequency of a disease and its related risk factors at a certain period of time

"What is happening"

Cross sectional study

2

cross sectional study measures

prevalence

3

compares a group with a disease to one without a disease and looks for any PRIOR risk factors

" What happened?

case control

4

compares a group with a given risk factor to a group without a risk factor and sees if the exposure will causes disease later
can be prospective or retrospective

"Who will develop"
"Who did develop"

cohort

5

experiment that involves humans that compares the therapeutic benefits od 2 or more treatments or of a treatment and a PLACEBO

clinical trial

6

phase 1

small number of healthy volunteers
" Is it safe?" asses the saftey, toxicity, pharmockinetisc and pharmacodynamics

7

phase 2

small number of people with the disease of interest

" Does it work"
do the treatment actually work and are there adverse effects

8

phase 3

large number of patients randomly assigned to a group
" Is it good or is it better?"
compares new treatment to current treatment standard

9

phase 4

postmarketting of drug surveillance
" Can it stay?"
what are the long term adverse effects

10

1-false negative =

sensitivity

11

1- false positive

specificcity