Flashcards in Observational Studies Deck (11):
1
collects data from a group of people to asses the frequency of a disease and its related risk factors at a certain period of time
"What is happening"
Cross sectional study
2
cross sectional study measures
prevalence
3
compares a group with a disease to one without a disease and looks for any PRIOR risk factors
" What happened?
case control
4
compares a group with a given risk factor to a group without a risk factor and sees if the exposure will causes disease later
can be prospective or retrospective
"Who will develop"
"Who did develop"
cohort
5
experiment that involves humans that compares the therapeutic benefits od 2 or more treatments or of a treatment and a PLACEBO
clinical trial
6
phase 1
small number of healthy volunteers
" Is it safe?" asses the saftey, toxicity, pharmockinetisc and pharmacodynamics
7
phase 2
small number of people with the disease of interest
" Does it work"
do the treatment actually work and are there adverse effects
8
phase 3
large number of patients randomly assigned to a group
" Is it good or is it better?"
compares new treatment to current treatment standard
9
phase 4
postmarketting of drug surveillance
" Can it stay?"
what are the long term adverse effects
10
1-false negative =
sensitivity
11