ANTIFUNGAL AGENTS Flashcards

(47 cards)

1
Q

What is Anidulafungin also known as?

A

Eraxis

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2
Q

What is the brand name for Amphotericin B?

A
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3
Q

What are the brand names for Butoconazole?

A

Gynazole-1, Mycelex-3

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4
Q

What is the brand name for Butenafine?

A

Lotrimin Ultra, Mentax

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5
Q

What is Caspofungin also known as?

A

Cancidas

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6
Q

What are the brand names for Clotrimazole?

A

generic, Lotrimin

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7
Q

What is the generic name for Econazole?

A

generic, Spectazole

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8
Q

What is the brand name for Fluconazole?

A

Diflucan

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9
Q

What is Flucytosine also known as?

A

Ancobon

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10
Q

What are the brand names for Griseofulvin?

A

Grifulvin, Grisactin, Fulvicin P/G

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11
Q

What is the brand name for Itraconazole?

A

Sporanox

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12
Q

What is Ketoconazole also known as?

A

generic, Nizoral

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13
Q

What are the brand names for Miconazole?

A

generic, Micatin

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14
Q

What is Micafungin also known as?

A

Mycamine

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15
Q

What is the brand name for Naftifine?

A

Naftin

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16
Q

What is Natamycin also known as?

A

Natacyn

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17
Q

What are the brand names for Nystatin?

A

generic, Mycostatin

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18
Q

What is Oxiconazole also known as?

A

Oxistat

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19
Q

What is Posaconazole also known as?

20
Q

What is the brand name for Sulconazole?

21
Q

What are the brand names for Terbinafine?

22
Q

What are the brand names for Terconazole?

A

Terazol 3, Terazol 7

23
Q

What are antifungal agents?

A

Medications used to treat fungal infections

24
Q

How do antifungal agents work?

A

By targeting different aspects of fungal cells such as the cell membrane, cell wall, or enzymes involved in metabolism

25
Name the classes of antifungal agents.
* Azoles * Polyenes * Allylamines * Echinocandins
26
What is the main action of azoles?
Inhibit the synthesis of ergosterol
27
Give examples of azoles.
* Fluconazole * Itraconazole * Voriconazole
28
What do polyenes target?
The fungal cell membrane by binding to ergosterol
29
Name a common polyene antifungal.
Amphotericin B
30
What do allylamines inhibit?
Ergosterol biosynthesis
31
Name a common allylamine antifungal.
Terbinafine
32
What do echinocandins interfere with?
The synthesis of the fungal cell wall
33
What is the action of flucytosine?
Inhibits DNA and RNA synthesis in fungal cells
34
How do most antifungal agents work?
By interfering with the fungal cell membrane or cell wall
35
What is ergosterol?
A sterol that plays a crucial role in the fungal cell membrane
36
How do polyenes interact with ergosterol?
By binding to it, disrupting the cell membrane's integrity
37
What do echinocandins disrupt?
The synthesis of chitin in the fungal cell wall
38
What types of infections are treated by antifungal agents?
* Skin infections * Nail infections * Oral and vaginal infections * Systemic infections
39
Name some skin infections treated by antifungal agents.
* Athlete's foot * Ringworm * Jock itch
40
What is onychomycosis?
Nail infection
41
What are common oral and vaginal infections treated with antifungals?
* Thrush * Yeast infections
42
What are some important considerations for antifungal medications?
* Over-the-counter vs. prescription * Drug interactions * Adverse effects * Resistance
43
Which antifungals are available over-the-counter?
* Clotrimazole * Miconazole
44
Which antifungals typically require a prescription?
* Fluconazole * Voriconazole
45
Why is it important to inform your doctor about other medications when taking antifungals?
Antifungals can interact with other medications
46
What are some common adverse effects of antifungals?
* Nausea * Vomiting * Skin rash
47
What can prolonged or incomplete treatment of fungal infections lead to?
Antifungal resistance