CNS stimulants Flashcards
(14 cards)
What is the primary active component of marijuana?
Tetrahydrocannabinol (THC)
THC binds to cannabinoid receptors in the brain
What type of drug is cocaine classified as?
Local anesthetic, drug of abuse
Cocaine decreases reuptake and increases CNS levels of norepinephrine, dopamine, and serotonin
What conditions is dextroamphetamine used to treat?
Attention-deficit hyperactivity disorder, narcolepsy
It increases the release of epinephrine and norepinephrine and stimulates their receptors
What is MDMA commonly known as?
‘Ecstasy’
Methylenedioxymethamphetamine
It increases serotonin release in the CNS and is classified as a hallucinogen
What is the primary use of methylphenidate (Ritalin)?
Attention-deficit hyperactivity disorder
It is an amphetamine analog
What are methylxanthines?
Caffeine, Theobromine
They stimulate the CNS by antagonizing the inhibitory action of adenosine
What receptors does nicotine bind to?
CNS nicotinic receptors
This activation stimulates the dopaminergic brain reward pathways
What effects does phencyclidine (PCP) have?
Blocks NMDA type glutamate receptors, hallucinogen, anesthetic
PCP is known for its dissociative effects
What is modafinil (Provigil) classified as?
Sleep antagonist, amphetamine type
It blocks GABA transmission
What condition is Amphetamine commonly used to treat?
Narcolepsy
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness.
What effect does Amphetamine have on appetite?
↓ appetite
Amphetamines are known for their appetite-suppressing qualities.
Which receptors does Amphetamine stimulate?
α, β receptors
These receptors are types of adrenergic receptors that mediate various physiological responses.
How does Amphetamine affect MAO activity?
↓ MAO activity
MAO (monoamine oxidase) is an enzyme that breaks down neurotransmitters; its inhibition can increase levels of these neurotransmitters.
Name: CNS stimulants
Amphetamine Narcolepsy,
Cannabinoids (Marijuana) Tetrahydrocannabinol (THC),
Cocaine
Dextroamphetamine
MDMA-Methylenedioxymethamphetamine,
Methylphenidate (Ritalin)
Methylxanthines
Nicotine
Phencyclidine (PCP)