SULFONAMIDES FOR SPECIAL APPLICATIONS Flashcards
(15 cards)
What is Mafenide commonly known as?
Sulfamylon
What is the generic name for Silvadene?
Silver sulfadiazine
What is the generic name for Sulfacetamide sodium?
Sulfacetamide sodium
What are sulfonamides primarily known as?
Antibiotics
Sulfonamides have special applications beyond treating bacterial infections.
Name a condition treated with sulfasalazine.
Ulcerative colitis and Crohn’s disease
Sulfasalazine is a sulfonamide derivative.
How do sulfonamides help in treating urinary tract infections?
They concentrate in the urine
This property makes them effective against urinary tract infections.
List two topical uses of sulfonamides for burn treatment.
- Silver sulfadiazine
- Mafenide acetate
These are used topically for treating burns.
What is the use of vaginal creams containing sulfanilamide?
Treat vaginal infections
These creams and suppositories are effective for vaginitis.
What ophthalmic sulfonamide is used to treat superficial eye infections?
Sulfacetamide
It is used topically for superficial ocular infections.
Name a category of drugs that contains sulfonamide functional groups.
Diuretics
Some thiazide and loop diuretics contain this functional group.
Which sulfonamide is used in combination with pyrimethamine to treat malaria?
Sulfadoxine
It is used as an antimalarial.
What type of fungi have shown inhibitory activity against sulfonamides?
Pneumocystis carinii
Sulfonamides have antifungal properties.
Which protozoa are sulfonamides active against?
- Toxoplasma
- Coccidia
They are effective as antiparasitic agents.
What is the mechanism of action of sulfonamides?
They competitively inhibit dihydropteroate synthase (DHPS)
This enzyme is essential for bacterial folic acid synthesis.
Fill in the blank: Sulfonamides prevent bacterial growth by disrupting _______.
folic acid synthesis
This disruption is critical for bacterial multiplication.
