BETA-LACTAM COMPOUNDS PENICILLINS Flashcards

(27 cards)

1
Q

What is the generic name for Amoxil?

A

Amoxicillin

Amoxicillin is commonly used to treat bacterial infections.

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2
Q

What combination does Augmentin contain?

A

Amoxicillin/potassium clavulanate

Augmentin is often prescribed for its enhanced effectiveness against certain bacteria.

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3
Q

What is the generic name for Unasyn?

A

Ampicillin/sulbactam sodium

This combination is used for treating moderate to severe infections.

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4
Q

What is the generic name for Geocillin?

A

Carbenicillin

Carbenicillin is effective against certain Gram-negative bacteria.

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5
Q

What is the generic name for Dicloxacillin?

A

Dicloxacillin

Dicloxacillin is used to treat infections caused by penicillin-resistant bacteria.

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6
Q

What is the generic name for Nafcillin?

A

Nafcillin

Nafcillin is particularly effective against staphylococci.

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7
Q

What is the generic name for Oxacillin?

A

Oxacillin

Oxacillin is used to treat infections caused by penicillin-resistant Staphylococcus aureus.

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8
Q

What is the generic name for Pentids?

A

Penicillin G

Penicillin G is a natural penicillin used to treat a variety of infections.

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9
Q

What is the brand name for Penicillin G benzathine?

A

Permapen, Bicillin

This formulation is often used for long-acting penicillin therapy.

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10
Q

What is the generic name for V-Cillin?

A

Penicillin V

Penicillin V is commonly used for oral therapy of infections.

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11
Q

What is the generic name for Pipracil?

A

Piperacillin

Piperacillin is a broad-spectrum penicillin effective against Gram-negative bacteria.

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12
Q

What is the brand name for Piperacillin and tazobactam sodium?

A

Zosyn

Zosyn is often used for serious infections in hospitalized patients.

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13
Q

What is the generic name for Ticar?

A

Ticarcillin

Ticarcillin is used against certain Gram-negative bacterial infections.

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14
Q

What is the combination in Timentin?

A

Ticarcillin/clavulanate potassium

Timentin is effective against beta-lactamase producing bacteria.

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15
Q

What are penicillins?

A

A type of beta-lactam antibiotic characterized by a beta-lactam ring in their chemical structure.

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16
Q

What types of bacteria are penicillins effective against?

A

Both gram-positive and gram-negative bacteria.

17
Q

What is the mechanism of action of penicillins?

A

Disrupt the synthesis of the bacterial cell wall by interfering with the crosslinking of peptidoglycans.

18
Q

What do penicillins bind to in order to inhibit bacterial growth?

A

Penicillin-binding proteins (PBPs).

19
Q

What is the result of the disruption caused by penicillins?

A

Weakened bacterial cell walls leading to bacterial death.

20
Q

What are narrow-spectrum penicillins effective against?

A

A limited range of bacteria, often gram-positive organisms.

21
Q

Give two examples of narrow-spectrum penicillins.

A

Penicillin G and penicillin V.

22
Q

What are broad-spectrum penicillins effective against?

A

A wider range of bacteria, including both gram-positive and gram-negative organisms.

23
Q

Give two examples of broad-spectrum penicillins.

A

Amoxicillin and ampicillin.

24
Q

What are penicillinase-resistant penicillins designed to resist?

A

Inactivation by beta-lactamase.

25
Give three examples of penicillinase-resistant penicillins.
Oxacillin, cloxacillin, and dicloxacillin.
26
What are penicillin + beta-lactamase inhibitor combinations used for?
To overcome resistance to penicillins.
27
Give two examples of penicillin + beta-lactamase inhibitor combinations.
Amoxicillin-clavulanate and ampicillin-sulbactam.