TRIMETHOPRIM Flashcards
(14 cards)
What is Trimethoprim?
A medication used to treat bacterial infections
It is available under the brand names Proloprim and Trimpex.
What is Trimethoprim-sulfamethoxazole commonly known as?
Co-trimoxazole or TMP-SMZ
This combination is also marketed under the brand names Bactrim and Septra.
What are the brand names for Trimethoprim?
Proloprim, Trimpex
These are the commercial names under which Trimethoprim is sold.
What is the generic name for Bactrim?
Trimethoprim-sulfamethoxazole
Bactrim is a combination antibiotic medication.
What are the brand names for Trimethoprim-sulfamethoxazole?
Bactrim, Septra, others
This medication is used to treat a variety of infections.
What is Trimethoprim (TMP) primarily used to treat?
Bladder infections
Other uses include middle ear infections and travelers’ diarrhea.
With which medications can Trimethoprim be used to treat Pneumocystis pneumonia?
Sulfamethoxazole or dapsone
This is specifically for people with HIV/AIDS.
How is Trimethoprim administered?
Orally (swallowed by mouth)
What are common side effects of Trimethoprim?
- Nausea
- Changes in taste
- Rash
What rare blood problems can Trimethoprim cause?
- Not enough platelets
- Not enough white blood cells
What sensitivity may Trimethoprim cause?
Sun sensitivity
What is the evidence regarding Trimethoprim and pregnancy?
Potential harm during pregnancy in some animals but not humans
What mechanism does Trimethoprim use to inhibit bacterial growth?
Blocks folate metabolism via dihydrofolate reductase in some bacteria
What does blocking folate metabolism lead to in bacteria?
Prevention of bacterial DNA and RNA creation, leading to bacterial cell death
