INTERMEDIATE-SPECTRUM (SECOND-GENERATION) CEPHALOSPORINS Flashcards
(20 cards)
What is the generic name for Ceclor?
Cefaclor
Cefaclor is an antibiotic used to treat various infections.
What is the brand name for Cefmetazole?
Zefazone
Cefmetazole is a cephalosporin antibiotic.
What is Cefotetan commonly known as?
Cefotan
Cefotetan is used for treating infections and is a second-generation cephalosporin.
What is the brand name for Cefoxitin?
Mefoxin
Cefoxitin is effective against certain types of bacteria and is often used in surgical prophylaxis.
What is the brand name for Cefprozil?
Cefzil
Cefprozil is used to treat infections caused by bacteria.
List the brand names associated with Cefuroxime.
- Ceftin
- Kefurox
- Zinacef
Cefuroxime is a second-generation cephalosporin antibiotic.
What are second-generation cephalosporins also known as?
Intermediate-spectrum cephalosporins
How do second-generation cephalosporins compare to first-generation cephalosporins in terms of activity against gram-negative bacteria?
They enhance their activity against gram-negative bacteria
List three gram-negative bacteria that second-generation cephalosporins are effective against.
- Neisseria gonorrhoeae
- Enterobacter aerogenes
- Escherichia coli
Which gram-positive bacteria can be treated with second-generation cephalosporins?
Staphylococcus aureus
Name an example of an oral second-generation cephalosporin.
Cefaclor
What are two forms in which cefuroxime is available?
- Oral (axetil)
- Parenteral (sodium)
What is a notable feature of cefuroxime?
Ability to cross the blood-brain barrier
What type of coverage does cefoxitin provide?
Anaerobic coverage
What infections are second-generation cephalosporins commonly used to treat?
- Urinary tract infections
- Pneumonia
- Skin and soft tissue infections
What is a limitation of second-generation cephalosporins?
They generally lack activity against Pseudomonas aeruginosa
Fill in the blank: Second-generation cephalosporins are effective against some strains of _______.
Staphylococcus aureus
Which second-generation cephalosporin is known for its anaerobic coverage?
Cefotetan
True or False: Second-generation cephalosporins have better activity against gram-positive bacteria than first-generation cephalosporins.
False
What additional gram-negative organisms can second-generation cephalosporins target compared to first-generation?
- Indole-positive Proteus
- Klebsiella
