Lecture 07: Spermatogenesis (Pozor) Flashcards Preview

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Flashcards in Lecture 07: Spermatogenesis (Pozor) Deck (23)
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1
Q

spermatogenesis

A

formation of spermatozoa from spermatogonia (proliferation)

2
Q

spermatocytogenesis

A

mitotic divisions involving proliferation and maintenance of spermatogonia

3
Q

meiosis in spermatogenesis

A

reduction of genetic material. Involves primary and secondary spermatocytes

4
Q

spermiogenesis

A

morphologic transformation of spherical spermatids into spermatozoa (differentiation)

5
Q

chromosomes/chromatids in primary and secondary spermatocytes, spermatids, and spermatozoa?

A

primary: 2n,4C
secondary: 1n, 2C (because meiosis I has occured)
spermatids: 1n, 1c (because meiosis II has occured)
spermatozoa: 1n, 1c

6
Q

role of centrioles in spermatogenesis

A

well organized tubules that move toward nuclear pole and help form tail and system of attachment for tail in sperm

7
Q

4 phases of spermiogenesis

A

1) Golgi
2) Cap
3) Acrosomal
4) Maturation

8
Q

Golgi phase of spermiogenesis

A

1st phase. formation of acrosomic granule

9
Q

Cap phase of spermiogenesis

A

2nd phase. growth of acrosomic head cap

10
Q

Acrosomal phase of spermiogenesis

A

3rd phase. condensation, elongation, shaping of sperm

11
Q

Maturation phase of spermiogenesis

A

4th and final phase. final formation of flagellum and neck piece, final condensation and shaping of nucleus

12
Q

Where is estrogen produced in the male?

A

tail of epididymis

13
Q

Importance of disulfide crosslinking in spermatogenesis

A

allows DNA to be densely packed into sperm heads

14
Q

What do sertoli cells produce?

A

inhibin and activin

15
Q

what do leydig cells?

A

testosterone

16
Q

Main hormone involved in spermatogenesis (especially to initiate it) ****

A

FSH

17
Q

what inhibits FSH?

A

inhibin

18
Q

What does LH do in spermatogenesis?

A

stimulate leydig cells to produce testosterone

19
Q

Role of FSH in spermatogenesis

A

acts on sertoli cells, causing them to release estrogen, DHT, inhibin

20
Q

Which hormones have negative feedback to AP during spermatogenesis?

A

Inhibin, testosterone

21
Q

What does endpiece of sperm’s tail lack?

A

axoneme (cytoskeletal core) and fibrous sheath

22
Q

Sperm tail organization

A

9+2 axoneme (central unpaired doublet surrounded by 9 paired doublets of microtubules arranged like spokes on a wheel)

23
Q

dynein

A

motor protein that contributes to whip-like motion of sperm’s tail

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