Lecture 07: Spermatogenesis (Pozor) Flashcards Preview

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Flashcards in Lecture 07: Spermatogenesis (Pozor) Deck (23):
1

spermatogenesis

formation of spermatozoa from spermatogonia (proliferation)

2

spermatocytogenesis

mitotic divisions involving proliferation and maintenance of spermatogonia

3

meiosis in spermatogenesis

reduction of genetic material. Involves primary and secondary spermatocytes

4

spermiogenesis

morphologic transformation of spherical spermatids into spermatozoa (differentiation)

5

# chromosomes/chromatids in primary and secondary spermatocytes, spermatids, and spermatozoa?

primary: 2n,4C
secondary: 1n, 2C (because meiosis I has occured)
spermatids: 1n, 1c (because meiosis II has occured)
spermatozoa: 1n, 1c

6

role of centrioles in spermatogenesis

well organized tubules that move toward nuclear pole and help form tail and system of attachment for tail in sperm

7

4 phases of spermiogenesis

1) Golgi
2) Cap
3) Acrosomal
4) Maturation

8

Golgi phase of spermiogenesis

1st phase. formation of acrosomic granule

9

Cap phase of spermiogenesis

2nd phase. growth of acrosomic head cap

10

Acrosomal phase of spermiogenesis

3rd phase. condensation, elongation, shaping of sperm

11

Maturation phase of spermiogenesis

4th and final phase. final formation of flagellum and neck piece, final condensation and shaping of nucleus

12

Where is estrogen produced in the male?

tail of epididymis

13

Importance of disulfide crosslinking in spermatogenesis

allows DNA to be densely packed into sperm heads

14

What do sertoli cells produce?

inhibin and activin

15

what do leydig cells?

testosterone

16

Main hormone involved in spermatogenesis (especially to initiate it) ******

FSH

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what inhibits FSH?

inhibin

18

What does LH do in spermatogenesis?

stimulate leydig cells to produce testosterone

19

Role of FSH in spermatogenesis

acts on sertoli cells, causing them to release estrogen, DHT, inhibin

20

Which hormones have negative feedback to AP during spermatogenesis?

Inhibin, testosterone

21

What does endpiece of sperm's tail lack?

axoneme (cytoskeletal core) and fibrous sheath

22

Sperm tail organization

9+2 axoneme (central unpaired doublet surrounded by 9 paired doublets of microtubules arranged like spokes on a wheel)

23

dynein

motor protein that contributes to whip-like motion of sperm's tail

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