Respiration Lecture 08: Distribution of Ventilation and Lung Perfusion Flashcards Preview

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Flashcards in Respiration Lecture 08: Distribution of Ventilation and Lung Perfusion Deck (16):
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Hypoxemia

low blood oxygen

1

2 main causes of hypoxemia

1) increase in thickness of diffusion barrier due to i.e. infection, edema, pulmonary hypertension, swelling
2) loss of surface area of diffusion barrier

2

more negative Ppl --> PTP?

PTP also becomes more negative

3

Which area of the lung is most ventilated?

basal region due to gravity

4

Is PO2 greater in apical or basal region?

apical

5

Is PCO2 greatest in apical or basal region of lung?

basal

6

Why does L heart generate larger pressure than R heart?

Must supply blood to all of systemic circulation

7

increased lung volume --> alveoli and capillaries?

Alveoli expand, capillaries tend to collapse

8

*Gravity prevent regional collapse of pulmonary capillaries*

.

9

transit time

amt. of time a bollus of blood sits in gas exchange space.

10

Increased cardiac output --> transit time

increases(?)

11

What percent of cardiac output goes through pulmonary vasculature?

100%

12

4 main functions of pulmonary vasculature

1) acts on all blood contents
2) filters
3) regulates blood enzymes
4) activates/deactivates venous molecules

13

Ventilation to perfusion ratio (VA/Q)

estimates the match between blood perfusion of a pulmonary capillary around an alveolus and the ventilation of the alveolus

14

bronchial circulation

part of systemic circulation that provides oxygenated systemic blood to the bronchi. Doesn't usually get into gas exchange areas

15

Physiological Dead Space****

-alveolar regions of the lung that are ventilated but don't have blood flowing through the adjacent pulmonary capillaries.
-Doesn't participate in gas exchange
-Combination of ANATOMICAL dead space + ventilated but unperfused alveoli
-Will always exceed anatomical dead space

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