Respiration Lecture 08: Distribution of Ventilation and Lung Perfusion Flashcards Preview

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Flashcards in Respiration Lecture 08: Distribution of Ventilation and Lung Perfusion Deck (16)
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0
Q

2 main causes of hypoxemia

A

1) increase in thickness of diffusion barrier due to i.e. infection, edema, pulmonary hypertension, swelling
2) loss of surface area of diffusion barrier

1
Q

Hypoxemia

A

low blood oxygen

2
Q

more negative Ppl –> PTP?

A

PTP also becomes more negative

3
Q

Which area of the lung is most ventilated?

A

basal region due to gravity

4
Q

Is PO2 greater in apical or basal region?

A

apical

5
Q

Is PCO2 greatest in apical or basal region of lung?

A

basal

6
Q

Why does L heart generate larger pressure than R heart?

A

Must supply blood to all of systemic circulation

7
Q

increased lung volume –> alveoli and capillaries?

A

Alveoli expand, capillaries tend to collapse

8
Q

Gravity prevent regional collapse of pulmonary capillaries

A

.

9
Q

transit time

A

amt. of time a bollus of blood sits in gas exchange space.

10
Q

Increased cardiac output –> transit time

A

increases(?)

11
Q

What percent of cardiac output goes through pulmonary vasculature?

A

100%

12
Q

4 main functions of pulmonary vasculature

A

1) acts on all blood contents
2) filters
3) regulates blood enzymes
4) activates/deactivates venous molecules

13
Q

Ventilation to perfusion ratio (VA/Q)

A

estimates the match between blood perfusion of a pulmonary capillary around an alveolus and the ventilation of the alveolus

14
Q

bronchial circulation

A

part of systemic circulation that provides oxygenated systemic blood to the bronchi. Doesn’t usually get into gas exchange areas

15
Q

Physiological Dead Space**

A
  • alveolar regions of the lung that are ventilated but don’t have blood flowing through the adjacent pulmonary capillaries.
  • Doesn’t participate in gas exchange
  • Combination of ANATOMICAL dead space + ventilated but unperfused alveoli
  • Will always exceed anatomical dead space

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