Chapter 18 Endocrine Glands Part 1 Flashcards

(84 cards)

1
Q

what two glands integrate 2 body controlling systems and which systems

A

hypothalamus and pituitary gland

nervous and endocrine

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2
Q

what regulates pituitary gland secretion in response to other hormones, sensory info, emotions

A

hypothalamus

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3
Q

where is the hypothalamus located

A

base of brain witch direct connection to pituitary via infundibulum

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4
Q

hypothalamus regulates anterior pituitary via what

A

blood vessels, where 2 capillary networks are connected by portal veins

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5
Q

the hypothalamus regulates posterior pituiatary via what

A

neural pathway through infundibulum

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6
Q

the tract in the posterior pituitary arises from what

A

neurons in paraventricular and suporaoptic nuclei of hypothalamus

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7
Q

nerves or clusters of brain cells

A

nuclei

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8
Q

what sits in sella turcica of sphenoid bone

A

pituitary gland

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9
Q

the pituitary gland have arterial blood supply via what

A

hypophyseal branches of internal carotid arteries

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10
Q

where do the veins in the pituitary gland drain into

A

dural sinuses

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11
Q

what is an adenohypophysis

A

anterior pituitary

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12
Q

Glandular epithelium develops as outpocket of roof of oral cavity (Rathke pouch / Pituitary diverticulum), Connection to oral cavity severed. ONLY vascular connection to Hypothalamus via Hypophyseal Portal Veins.

A

anterior pituitary

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13
Q

anterior pituitary portal system

A

capillary bed to veins to 2nd capillary bed

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14
Q

what is the role of the pituitary gland

A

releasing and inhibiting hormones in ventral hypothalamus to anterior pituitary quickly

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15
Q

what borders post pituitary and has no function in adult, in fetus it produces MSH, role in lower vertebrates

A

pars intermedia

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16
Q

Neurohypophysis with Infundibulum; Part of the Brain

A

posterior pituitary

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17
Q

what is the posterior pituitary composed of

A

neural tissue pituicytes and nerve fibers

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18
Q

what does neural tissue do

A

regulate release of hormones

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19
Q

what is continous with hypothalamus

A

PP

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20
Q

embryologic development=

A

outgrowth of the brain, infundibulum enlarges to form the posterior pituitary

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21
Q

what does the PP release

A

neurohormones and neuropeptides

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22
Q

the pituitary gland stores hormones but not a

A

endocrine gland

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23
Q

what does the hypothalamic-hypophyseal tract do

A

carry hormones to pituitary

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24
Q

what do hypothalamic neurons synthesize

A

oxytocin and adh

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25
what controls secretion of posterior pituitary hormones
nerve stimulation in hypothalamus
26
AP’s conducted by Axons of Hypothalamic Neurons through Hypothalamic-Hypophyseal Tract to
posterior pituitary
27
what is transported down the Axons of Hypothalamic-Hypophyseal Tract to Posterior Pituitary
oxytocin and ADH
28
where are oxytocin and ADH stored
in axon terminals in PP
29
Hypothalamic Neurons fire & AP’s arrive at Axon terminals ->
oxytocin and ADH release into blood
30
once oxytocin and ADH are in the blood what happens
travel through it and bind to receptors on target cells to influence tissue activity
31
there are releasing and inhibiting hormones in anterior or posterior pituitary
anterior
32
releasing hormones=
stimulate anterior pituitary hormone secretion
32
inhibiting hormones=
inhibit anterior pituitary hormone secretion
33
hypothalamic neurons synthesize what in anterior pituitary
synthesize releasing or inhibiting hormones
34
neuron stimulation in hypothalamus controls secretion of releasing or inhibiting hormones into
primary capillary plexus of hypothalamus
35
hypothalamic hormones travel through the
portal veins to anterior pituitary
36
anterior pituitary secretes hormones into
secondary capillary plexus (in response to releasing hormones)
37
if it is inhibiting hormones it causes
prevention of hormone secretion
38
after it goes to capillary plexus
it travels via bloodstream and bind to receptors on target cells and influence tissue activity
39
what does growth hormone releasing hormone do
increase GH level
40
what does growth hormone inhibiting hormone do
inhibit GH and TSH secretion
41
what does thyrotrophin releasing hormone do
increase tsh level
42
what does corticotropin releasing hormone do
increase acth level
43
what does gonadotropic releasing hormone do
increase fsh and lh levels
44
what does prolactin inhibiting hormone do
inhibits prl secretion
45
what is nervous tissue only
posterior pituitary
46
antidiuretic hormone is also called
vasopressin
47
vasopressin causes increase of what with signficiant secretion
BP
48
what is ADH role
maintains water balance, causes water resorption and prevents urine formation
49
what does ADH act on
kidney tubules
50
ADH is triggered by
pain low bp nicotine morphine barbituates
51
what is adh made by
neuron cell bodies in SO nuclei of hypothalamus, stores in post pit.
52
inference of adh:
surgical removal of post. pit. which results in hormone shortage
53
rate of secretion is dependent on response to changes in what?
blood osmolality and blood volume
54
what detects changes in blood osmolality
osmoreceptors
55
what detect changes in bp
baroreceptors
56
if osmolality increases and bp decreases what happens to ADH secretion
ADH secreting neurons increase APs
57
osmotic concentration = number of solute in 1 kg of water x number of particles into which solute dissociates- directly proportionate to concentration of solutes
osmolality
58
APs go to the post. pit. causing ADH to be released into the blood and causes what to increase
kidney tubules increase water resoprtion
59
kidney tubules increase water resoprtion which results in
reduced urine amount, increases urine osmalality and decreased loss of blood volume
60
adh secretion is inhibited by
xs water, diurectics, alcohol
61
what is from an ADH deficiency, extreme thirst and frequent urination with high urinary output
diabetes insipidus
62
what causes diabetes insipidus
pit tumor head trauma = damage to hypothalamus or post pit
63
if the patient with diabetes insipidus has the capacity to drink enough water to prevent dehydration then will they be ok
yes
64
what causes a patient to have a life threatening cause of diabetes insipidius
the patient is compromised and unconscious or in a come
65
what is SIADH
syndrome of inappropriate ADH secretion
66
what is SIADH due to
neurosurgery cancer certain meds general anesthesia
67
symptoms of SIADH
brain edema-> fluid retention, headache, disoriented, weight gain, blood dilution
68
how do you treat SIADH
fluid restriction follow Na level slowly correct level or central pontine myelinolysis
69
what is made by neuron cell bodies in PV nuclei of hypothalamus and stored in post pit
oxytocin
70
pos feedback for oxytocin
stimulates uterine contraction in childbirth breastfeeding used to stop postpartum bleeding
71
what is a love hormone
oxytocin
72
what stimulate other glands (endocrine to endocrine), regulate secretory action; basophil cells
tropic hormones
73
what does thyroid stimulating hormones do
increase TH levels help with normal development maintain metabolism
74
what does adrenocorticotropic hormones do
stimulates adrenal cortex to increase glucocorticoid hormone secretion
75
when do levels of ACTH peak
in the AM
76
what trippers ACTH
fever hypoglycemia stress
77
what is a precursor for ACTH
proopiomelanocortin
78
how many molecules in proopiomelanocortin cleaved into
four
79
what does follicle stimulating hormone in females do
follicle maturation estrogen secretion in ovary
80
what does FSH in males do
produce sperm in testes
81
what does LH do in females
ovulation and progesterone secretion
82
what does LH do in males
produce testosterone in interstitial cells stimulates gonads
83