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Flashcards in Medical consequences of alcohol excess Deck (18):
1

Where has one of the fastest growing chronic liver disease and cirrhosis death rates in the world?

Scotland

2

How many admissions to hospital is alcohol responsible for

1 in 20

3

Who is the worst for alcohol drinking in scotland

Men in deprived areas

4

What are some acute effects of alcohol

CNS - accidents and violence
Gastro - oesophagitis, gastritis, ulceration, acute pancreatis
Respiratory - alcohol poisoning in overdose, aspiration
Behaviousral - anxiolysis, mood changes, errors in judgement - suicide, homicides, STDs

5

What are some of the good effects of high-risk drinking?

Decreases risk of RA
Increases HDL cholesterol
Decreased risk of kidney or gall stones
Lowers risk of diabetes

6

What are some of the effects of chronic heavy drinking?

Gastro - sotmach, liver, pancreas
CNS - neuropathies, dementia, Weknick-Korsakoff's syndrome
Cardio - hypertension, cardiomyopathy, MI, Stroke
Haematological - anaemia, bone marrow depression
Musculoskeletal - proximal myopathy, oestroporesis
Endocrine - cushion's syndrome
dermatological
reproductive - increased chance of miscarriage or congenital defects

7

What are the results of fetal alcohol syndrome

Growth deficiency
Mental retardation
intellectual impairment
attentional learning disabilities
behavioural problems

8

What are 3 beneficial effects of moderate alcohol use

Cardiovascular risks decrease, gall stones and potential beneficial effects

9

Name the 3 key components in alcohol metabolism in order

Alcohol dehydrogenase
Aldehyde dehydrogenase
Ketone bodies

10

What causes the variety in the way different people metabolise alcohol

Different levels of phase 2 enzymes

11

How likely is it for alcoholics to develop alcoholic fatty liver disease

90%

12

How likely is it for alcoholics to develop alcohol related cirrhosis

30%

13

What might alcoholic hepatitis appear as

Cholestatic

14

At what stage is it most likely that hepatitis will occur in Alcoholic liver disease

Any stage - steatosis or cirrhosis

15

What are the signs of chronic liver disease and portal hypertension

Encepalopathy
prolonged prothrombin time
hypoalbuminaemia
caput medusa
hypersplenism

16

How do we grade cirrhosis

Child's Turcotte-Pugh and MELD scores

17

What is the worst grade of this score

Grade C

18

What has been the biggest cause of the decrease in alcohol problems

The increase in cost - minimum price per unit

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