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Flashcards in Sepsis Deck (21):
1

What are some symptoms of intra-abdominal infection

Pain
Tenderness
Constipation or diarrhoea
Fever
Rigors/ chills
Nausea or vomiting
Anorexia
Malaise

2

What is the definition of Sepsis

A non-specific clinical response include 2 of the following:
Temp >38 or 90
Resp rate >20
WCC >12000/mm or <4000 mm

3

What might mimic sepsis (4)

Trauma
Burns
Pancreatitis
Other inflammatory processes

4

What is the importance of diagnosing sepsis early

To prevent severe sepsis and septic shock

5

What do we aim to achieve on the ward with regards to sepsis

Early recognition and intervention

6

What 3 things should be taken from the patient if the patient is septic

Blood cultures
Full blood count and lactate
Measure urine output

7

What 3 things do we give to a septic patient

Fluids
Antibiotics
Oxygen

8

What other diagnoistic tools can we use

Serological testing
Nucleic acid amplification

9

What else can we measure in blood science

FBC
U and E
LFT
CRP
Plasma viscosity
Amylase

10

What do we look for in blood cultures?

Bacteraemia

11

What is the main bug we need to consider when considering intra-abdominal infection

E Coli

12

What are strict aerobes

Organisms that require oxygen for growth, such as Pseudomonas sp.

13

What are aerobic organisms?

Organisms that grow better with oxygen, but can also grow without it, e.g. Staphylococci, Streptococci etc.

14

What are the majority of pathogens in the human body

Aerobic organisms

15

What part of the GI tract is usually sterile?

Stomach, bile duct

16

What antibiotics should be used to treat peritonitis, biliary tract or intra-abdominal infection

IV amoxicillin and metronidazole and gentamicin

17

What are sensitive to amoxicillin

Gram positive aerobes

18

What is senstive to gentamicin

Coliforms (E-Coli

19

What is sensitive to metronidazole

Anaerobes e.g. Bacteroides sp.

20

What is septic sohck

Severe sepsis with hypotension refractory to adequate volume resuscitation or requiring vasopressors or inotropes

21

What needs to be done for a perforated colonic diverticulum

Surgical resection

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