Lipid Digestion Flashcards Preview

Gastro > Lipid Digestion > Flashcards

Flashcards in Lipid Digestion Deck (23):
1

What percentage of energy requirement is provided by ingested lipids?

55%

2

What do ingested lipids comprise of?

Fats / Oil, phospholipids, cholesterol and cholesterol esters and fatty acids

3

Describe the solubility of ingested lipids

Insoluble or poorly soluble in water

4

What does gastric lipase do?

hydrolyses one of the 3 fatty acid tails

5

What is the significance of the double bonds and the length of the chains?

The length and strength of the molecule

6

What do fatty acids act as

Surfactant

7

What is CCK

A gut hormone

8

WHat is the role of bile salts

to confer polarity (polar charge) onto lipid molecules, act as detergents to emulsify large lipid drops to small droplets

9

Where are bile salts sectred from

Bile from the gall bladder

10

Bile salts are amphipathic. define this

hydrophilic group and hydrophilic group

11

What happens in failure to secrete bile salts

lipid malabsoption - steatorrhoea (fat in faeces) this can lead to secondary vitamin deficiency due to failure to absorb lipid soluble vitamins (ADEK)

12

What is the main purpose of the bile salts

To increase the surface area for action of lipase

13

What does the increased surface area allow for

Attack by pancreatic lipase

14

What does the increased surface area block?

access of the enzyme to the lipid with the hyrophobic core of the small droplets

15

Where are the final products of lipid digestion stored and released from?

Mixed Micelles

16

Where do short chain and medium chan fatty acids diffuse through>

Enterocyte

17

Where do short chains and medium chain fatty acids exit through?

The basolateral membraine and enter the villus capillaries

18

How long are long chain fatty acids ?

>12 Carbons

19

Where are long chain fatty acids resynthesised?

In the Endoplasmic Reticulum

20

What does Apolipoprotein do

Apolipoprotein coats the lipid mecellls and forms a chylomicron

21

Where does chylomicron enter the systemic circulation and how

into the subclavian vein via through the thoacic duct

22

Where do chylomicron triglyceride metabolised in capillaries by lipoprotein lipase present?

Endothelial cells

23

What is the role of albumen?

To distribute fatty acids and glycerol to be carried away to tissues

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