Flashcards in BL- COAG MADE EASY Deck (15):
The PT and the PTT pathway meet at factor:
X, because “X” marks the spot
Factor______is a cofactor for factor X, and you can remember this because ______fits into the notch of the X
Factor Xa converts prothrombin (Factor II) into ______, the most important enzyme on the planet
Thrombin, among other things, converts the soluble molecule fibrinogen into a:
solid fibrin clot
The Common Pathway money memory device
$ Small Bills: 10, 5, 2, 1
V + X
II = prothrombin
I = fibrinogen
You can remember the factors in the common pathway by remembering the bills in your wallet smaller than a ______. Don’t forget the $2 bill !!
Factor Xa converts ______ (Factor II) into thrombin, the most important enzyme on the planet
PT has one less letter than PTT, and PT values are shorter than PTT values, because the pathway is______
Well, just remember that the PTT is a basic ______of hematology.
Factor______converts prothrombin (Factor II) into thrombin, the most important enzyme on the planet
_______ converts the soluble molecule fibrinogen into a solid fibrin clot
Deficiency of___________will prolong the PT but not the PTT
Deficiencies of Factors ____________ will prolong the PTT and not the PT.
Remember that factor 10 is in the common pathway, and affects BOTH the PT and the PTT
12, 11, 9 and 8
Deficiencies of factor XI, IX, VIII, VII. X, V, prothrombin and fibrinogen are clinically significant.
Inhibitors of these factors are clinically significant for bleeding.