First Aid Pathology Flashcards Preview

BL/DD USMLE and Basics > First Aid Pathology > Flashcards

Flashcards in First Aid Pathology Deck (12):
1

Apoptosis

Programmed cell death
No inflammation

Cell shrinkage
Nuclear shrinkage
membrane blebbing
nuclear fragmenting

2

Necrosis

enzymatic degradation and protein denaturing from exogenous injury

Inflammatory process

3

Reversible cell injury

decreased atp synth
cell swelling
chromatin clumping
fatty changes
ribosomal detachment

4

Irreversible Cell injury

Ca influx (caspase activation)
Plasma membrane damage
Lysosomal rupture
mitochondria permeability

5

Inflammation characteristics

rubor- reddness
dolor- pain
calor- heat
tumor- swelling

6

Vascular inflammation response

increased vascular permeability
endothelial injury

7

Cellular inflammation response

neutrophils leave circulation to injury
Cause inflammation by:
Phagocytosis
degranulation
inflammatory mediator release

8

Acute Inflammation indicators

neurophiles
eosinophils
antibody mediated

9

Chronic Inflammation indicators

destruction and repair
Blood vessel proliferation
Fibrosis
Macrophages/giant cells
(mononuclear cell mediated)

10

Free radical cell injury

membrane lipid peroxidation
protein modification
DNA damage

11

Transudate

specific graviety <1.02
hypocellular/protein poor

12

Exudate

specific graviety >1.02
Cellular/protein rich