PATHOMA- vasculitis Flashcards Preview

BL/DD USMLE and Basics > PATHOMA- vasculitis > Flashcards

Flashcards in PATHOMA- vasculitis Deck (20):
1

vasculitis is defined as

inflammation of the blood vessel wall

2

general symptoms of vasculitis

non specific inflammation symptoms
organ ischemia

3

vasculitis is split into

vessel size

4

large vessel vasculitis type

temporal (giant cell) arteitis
takayas arteitis

*Aorta an its major branchs

5

Medium vessel vasculitis type

polyarteritis nodosa
kawasaki disease

*muscular art that supply organs

6

Small vessel vasculitis type

Wegener granulomatosis
Microscpoic Polyangitis
Chug Strous Small Cell
Henoch–Schönlein purpura

7

Adults over 50
Temporal artery (HA)
Opthalmic artery (vision chnages)
Jaw Claudation

temporal (giant cell) arteitis

8

Adults under 50
usually Asian women
Affctes proximally
neuro involvement

takayas arteitis

9

Elevated ESR
Granulomitis Inflamation
Presence of giant cells on biopsy

temporal (giant cell) arteitis/takayas arteitis

10

Young Adult
Necrotizing
Lungs are spared
affects large organs
related to Hep B

Polyaritis Nodosa

11

Asain children under 4
non-specific symptoms
Coronary Art
Can lead to MI Aspirin as Rx

kawasaki disease

12

takayas arteitis

Adults under 50
usually Asian women
Affctes proximally
neuro involvement

13

Never has lung symptoms
Nodules of fibrosis on artery tissue
FATAL without corticosteriod treatment

Polyaritis Nodosa

14

Wegener Granulomatosis

Wegener Granulomatosis

15

ANCA Test

Slide with neutrophils
add pt serum
if serum has AB, it will bind

P-ANCA- binds near nucleus
C-ANCA- binds in cytoplasm

16

Looks like Wegener Granulomatosis
Affects lung and kidney
P-ANCA+

Microscopic Polyangitis

17

IgA-IC deposition
common in children
has Palipable Purpura
IgA nephropathy
Often after a URI

Henoch–Schönlein purpura

18

Which vasculitis is P-ANCA and related to asthma?

Chug Strous Small Cell

19

Wegener Granulomatosis

Wegener Granulomatosis

20

Microscopic Polyangitis

Looks like Wegener Granulomatosis
Affects lung and kidney
P-ANCA+