DD- COMMON SKIN TUMORS (BENIGN) Flashcards Preview

BL/DD USMLE and Basics > DD- COMMON SKIN TUMORS (BENIGN) > Flashcards

Flashcards in DD- COMMON SKIN TUMORS (BENIGN) Deck (37):
1

Typically arise in middle age
MOST common vascular tumor in adults
Generally no association with underlying disease
Usually on the trunk

Cherry Hemangiomas SENILE CHERRY ANGIOMAS

2

Cherry Hemangiomas Treatment

Superficial electrodesiccation

Liquid nitrogen followed by curettage

Shave biopsy

Pulse dye laser- best for small lesions

3

The most common soft tissue tumor of infancy (10-12% of infants)
Benign endothelial cell neoplasm

Infantile Hemangioma
CAPILLARY HEMANGIOMA

other names:STRAWBERRY HEMANGIOMA, CAPILLARY HEMANGIOMA

4

Infantile Hemangioma- Complications

Ulceration
Size- may obstruct vision or feeding
Congenital syndromes (PHACES)

5

Infantile Hemangioma - Treatment Options

Observation

Local wound care

Pulsed dye laser

Topical, intralesional and systemic steroids

Beta-blockers

6

Stain with Glut-1, a placental antigen
More common in:
Girls
Premature infants

Infantile Hemangioma
STRAWBERRY HEMANGIOMA, CAPILLARY HEMANGIOMA

7

Vascular malformation
Present at birth
Persists into adulthood
Often irregular vascular channels that do NOT stain with Glut-1
Somatic mutation in GNAQ

Port Wine Stain
CAPILLARY MALFORMATION

8

Port Wine Stain- Complications

Overgowth of an extremity covered by a large port wine stain

Varicose veins, venous stasis, edema, ulceration

9

Port Wine Stain Treatment

Pulsed dye laser

Why treat?
Persist into adulthood
Get worse with time
Dark purple, nodular, bleeding blebs

10

Often only a precursor lesion is noted at birth, occasionally fully formed
Rapid proliferation in the first 1-3 months of life
Spontaneous involution over years

Infantile Hemangioma

11

Stain with Glut-1

nfantile Hemangioma

12

do NOT stain with Glut-1

Port Wine Stain

13

Hemangioma vs Port Wine gender

Hemangioma - girls
Port Wine- none

14

Klippel-Trenaunay syndrome

Port Wine on legs
may cause edema

15

Sturge Weber Syndrome

Port Wine on face
ocular and neurologic abnormalities including glaucoma, seizures and developmental delay

16

hamartoma
presents as a papillomatous yellow-orange plaque on face/scalp

Somatic mutations in HRAS and KRAS

Nevus Sebaceus

17

Nevus Sebaceus

enlargement of sebaceous glands

18

Nevus Sebaceus Treatment Options

Observation
Surgical excision

19

Common benign tumor of oil gland
Increasing frequency after middle age

Distribution- face>trunk>extremities

Sebaceous Hyperplasia

20

Sebaceous Gland Hyperplasia Treatment

No treatment
cosmetic issue only

21

Acrochordon
SKIN TAGS, FIBROEPITHELIAL POLYPS

Common- ¼ of all adults have at least one
Solitary or multiple

Soft, flesh-colored tan to brown exophytic papule (1-4 mm) with narrow base

22

benign tumor of adipose tissue.
It is the most common form of soft tissue tumor.
oft to the touch, usually movable, and are generally painless.

Lipoma

23

Lipoma Treatment options

No treatment
Surgical excision

24

Positive dimple (Fitzpatrick) sign
Complications- pain, pruritus
Distribution- legs
Typically solitary

Dermatofibroma

25

It is a result of an overgrowth of granulation tissue (collagen type 3) at the site of a healed skin injury which is then slowly replaced by collagen type 1.

Keloid Scar

26

Keloid Scar Rx

Topical steroids under occlusion
Intralesional steroids
Surgical excision: works best for ear keloids
Surgery +/- Radiation

27

Seborrheic Keratosis are called?

“Barnacles of Life”

Benign tumor of the hair follicle
Distribution- primarily head, neck, trunk

28

Seborrheic Keratosis
Clinical Variants

Dermatosis papulosa nigra
Stucco keratosis
Inflamed seborrheic keratosis
Sign of Leser-Trélat

29

Benign tumor of the hair follicle
Distribution- primarily head, neck, trunk

Seborrheic Keratosis

30

Seborrheic Keratosis Treatment

Moisturizers
Cryosurgery- treatment of choice

31

Infancy to adulthood
Any skin surface including mucous membranes
increased on sun-exposed skin

Nevocellular Nevi

32

Junctional Nevus are typically?

Flat macules

33

Compound Nevus are typically?

Papual/Nodule
Dark
on Trunk

34

Nevocellular Nevi
Treatment Options

Appropriate
Shave biopsy
Punch biopsy
Excision

35

Dysplastic Nevus

Acquired melanocytic proliferation
Round to oval to irregular
Variegation in color- tans, brown, black, reds
Margins- often indistinct

36


Neurofibromatosis Type 1:

Diagnosis requires 2 or more of the following criteria

1. 6+ café au lait macules > 1.5 cm

2. 2+ neurofibromas, or 1 plexiform neurofibroma

3. Axillary or inguinal freckling

4. Optic glioma

5. 2+ more Lisch nodules

6. osseous lesion or thinning of the long bone cortex

7. FDR with the disorder

37

Subtle increase in number of melanocytes with increased melanin production
Congenital or early childhood
Distribution- trunk and proximal extremities
Typically solitary
Multiple lesions associated with NF

Café-au-Lait Spots