Flashcards in PATHOMA- Derm inflam Deck (44):
Layers of the Epidermis
top to bottome
Stratum corneum contains?
Stratum spinosum contains?
a cell structure specialized for cell-to-cell adhesion. A type of junctional complex, they are localized spot-like adhesions randomly arranged on the lateral sides of plasma membranes.
key structural material making up the outer layer of human skin. It is also the key structural component of hair and nails.
The dermis contains
microscopic exocrine glands in the skin that secrete an oily or waxy matter, called sebum, to lubricate and waterproof the skin and hair of mammals
The basal cells functions to
Stem cell layer
Creates new epidermis
An itchy inflammation of the skin
also known as atopic eczema or eczema
inflammation of the skin
Atopic dermatitis key points
rx: topical steroids
results from exposure to allergens or irritants
caused by chemical irritants and those caused by physical irritants.
irritant contact dermatitis
manifestation of an allergic response caused by contact with a substance
allergic contact dermatitis
Common irritants in irritant contact dermatitis
rx: remove irritant from exposure
chronic inflammation of hair follicle and sebacous glands
acne vulgaris is caused by?
Hormones leading to increased sebum
*blocked follicle leading to infection by p. acne
Inflammation in Acne is the result of?
lipase breaks down xs sebum
release of inflammatory mediators
chronic, relapsing/remitting, immune-mediated systemic disease characterized by skin lesions including red, scaly patches, papules, and plaques, which usually itch.
Psoriasis lesions are?
also shows nail pitting
Psoriasis are located?
Psoriasis is caused by?
diffuse epidermal hyperplasia (thickening of the skin).
warm, tender, red, patch, plaque
dermis/sub q tissue
infection of the upper dermis and superficial lymphatics, usually caused by streptococcus bacteria on scratches or otherwise infected areas
rysipelas is more superficial than cellulitis, and is typically more raised and _______
minimal sub q
Stasis dermis location?
Seborrheic dermatitis location?
Atopic dermatitis location?
*may have arthritis
Lower ext. edema
Malassezia is a genus of fungi. Malassezia is naturally found on the:______
a filament-associated protein that binds to keratin fibers in epithelial cells.
Atopic derm etiology
Atopic derm is ass w/?
Allergic contact derm is a _____ rxn
Allergic contact derm is confirmed by?
______ may be ass. w/ cardiovascular disease