Diseases of infancy and childhood Flashcards Preview

Pathology > Diseases of infancy and childhood > Flashcards

Flashcards in Diseases of infancy and childhood Deck (25)
Loading flashcards...
1

[term]

intrinsic abnormal process, primary error of morphogenesis

malformation

2

[term]

amniotic band compressing parts of fetus

disruption

3

[term]

due to abnormal biomechanical process like that of club feet

deformations

4

[term]

one initiating aberration leading to cascade of anomalis

sequence

5

[term]

constellation of congenital anomalies that are pathologically related, cannot be explained by single, localized, initiating defects

malformation syndrome

6

[name the possible cause]

mental retardation, cataracts, sensorineural healing loss, cardiac anomalies

rubella

7

[name the possible cause]

short deformed limbs

thalidomide

phocomelia

8

[name tha possible cause]

microcephaly, growth retardation, facial anomalies, reduced mental capacity

alcohol

9

week of AOG that is extremely susceptible to teratogenesis

3rd to 9th week

10

pulmonary surfactant is composed of what compound?

dipalmitoylphsphatidylcholine (DPPC)

11

retinopathy of prematurity is due to ___ injury

hyperoxic

12

when to give glucocorticoids for lung maturity

24 to 34 weeks AOG

13

[disease entity]

premature, hematochezia, abdominal distension, circulatory collapse, pneumatosis intestinalis

necrotizing enterocolitis

14

mediator implicated in necrotizing enterocolitis because it increases mucosal permeability

platelet activating factor

15

most common cause of aplastic crisis in hemolytic anemia

parvovirus B19

16

[what disease entity]

congenital bilateral absence of vas deferens, dilated pancreatic and salivary duct, meconium ileus

cystic fibrosis

17

safest sleeping position in infatnts

supine

18

second most common malignancy in children

neuroblastoma

19

most common extracranial solid tumor of childhood

neuroblastoma

20

[what disease entity]

homer-wright pseudorosettes, small round blue cells with mitosis, karyorrhexis and atypia, neuropil

neuroblastoma

21

blueberry muffin baby, cross the midline

neuroblastoma

22

[name this syndrome]
organomegaly, macroglossia, hemihypertrophy, omphalocele, andrenal cytomegaly

beckwidth-weidemann

WT2 gene

23

[name this syndrome]
gonadal dysgenesis, early onset nephropathy (diffuse mesangial sclerosis), increased risk for wilms tumor

Denys-Drash Syndrome

WT1 gene

24

cross the midline, homer-wright pseudorosettes, neuropil, blue berry muffin

neurobalstoma

25

small round, blue cells, glands, glomerular sturcutres, fibroblastic stroma

wilms tumor