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Flashcards in Cellular Response to Stress Deck (10)
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1

Nuclear changes in necrosis

Pyknosis --> Karyorrhexis --> karyolysis

2

Pubertal breast changes is an example of physiologic ____ (hyperplasia/hypertrophy)

Hyperplasia

3

Architecture is not preserved in this kind of necrosis

caseous

4

In intrinsic pathway of apoptosis, BCL2 is ____ (activated, inactivated) while BAX/BAK channel is ____ (activated, inactivated)

Inactivated BCL2
Activated BAX/BAK

5

Caspase 8 and 10 are initiator caspases of which apoptotic pathway

Extrinsic

Intrinsic: Caspase 9

6

Executioner caspases are caspase ___ and ____

3 and 6

7

Intracellular hyaline that is PAS positive, diastase resistant is a characteristic of ___ disease

alpha 1 antitrypsin deficiency

8

PAS postive, diastase-sensitive glycogen granule in hepatocyte is characteristic of what disease?

DM

9

Onchronosis is due to the endogenous production of

Homogentisic acid (alkaptonuria)

10

Enzymes that are adapted to food deprivation, increases cellular longevity, and activation of DNA repair mechanism

sirtuins