Blood Vessels Pathology Flashcards Preview

Pathology > Blood Vessels Pathology > Flashcards

Flashcards in Blood Vessels Pathology Deck (39)
Loading flashcards...
1

[syndrome]

gain of function of ENaC channel resulting to increased Na reabsorption and then hypertension

Liddle Syndrome

2

Associated condition

eosinophilic hyaline material with associated luminal narrowing

essential hpn
DM

3

[associated condition]

concentric, laminated thickening, onion skin lesion, note of fibrinoid deposition and vessel wall necrosis

malignant hypertension

4

location of neovascularization in an atheromatous plaque

periphery

5

[clinical phase of atherosclerosis]

mural thrombosis, embolization, and wall thickening can lead to

aneurysm and rupture

6

[clinical phase of atherosclerosis]

plaque rupture, plaque erosion, plaque hemorrhage, mural thrombosis, embolization can lead to

occlusion by thrombus

7

[clinical phase of atherosclerosis]

progressive plaque growth can lead to

critical stenosis
(usually 70%)

8

the larger the lipid core, the ____stability of the plaque

greater the stability of the plaque

Remember, size of lipid core is inversely proportional to stability

9

the lesser the degree of inflammation, the ____ stability of the plaque

greater stability

remember, degree of inflammation is inversely proportional to stability

10

the thicker the fibrous cap, the ___ stable the plaque

more stable the plaque

fibrous cap is directly proportional to stability

11

[dissection]

intima tear involvinf the descending aorta only.

What is the standford classification?

Stanford B

DeBakey III = Standford B

12

[aortic dissection]

Both ascending and descending aorta are involved.

What is it s debakey classification?

DeBakey I

13

[diagnosis?]

45/M, hypertensive with marfan syndrome.

Noted sudden, excruciating anterior chest pain, radiating to the back and downward

aortic dissection

14

[syndrome]

Non-infectious small artery vasculitides, p-anca positive

churg-strauss syndrome

15

[syndrome]
non-infectious small artery vasculitides, c-anca positive

Wegener granulomatosis/ granulomatosis with polyangitis

16

[diagnosis]

headache among elderly individual, along course of superficial temporal artery, associated with multiple joint pains

giant cell arteritis

17

[diagnosis]

affects large vessels of the aortic arch, notable ocular disturbances and weakened UE pulses

takayasu

18

[diagnosis]

associated with hepatitis B, renal and visceral vessels (NEVER PULMONARY)

clinically, HPN and visceral ischemia

prominent fibrinoid necrosis, segmental, transmural, necrotizing

polyarteritis nodosa

19

[diagnosis]

fever >5 days, conjunctival injection, mucosal erythema, cervical lymphadenopathy, polyamorphous exanthem

kawasaki disease

20

important cause of MI in children; can cause coronary artery aneurysm

less prominent fibrinoid necrosis, segmental, transmural, necrotizing

kawasaki disease

21

[diagnosis]

associated with connective tissue disorders

common in kidney and LUNG; hemoptysis, hematuria

microscopic polyangitis

PAN = no lung involvement

22

[diagnosis]

associated with asthma, allergic rhinitis, eosinophilia

noted involvement of cutaneous, GIT, renal and cardiac vessel

Clinically, palpable purpura, GI bleed and FSGS

churg-strauss syndrome

23

[diagnosis]

PAN + extravascular necrotizing granulomas and hypereosinophilia

Churg-strauss syndrome

Remember, atopy/eosinophilia = sneeze = aaachooo = aaaachurg

24

[diagnosis]

fragmented PMNs in post capillary venule (leukocytolasia)

Microscopic polyangitis

25

[diagnosis]

prominent pulmonary involvement, may also involve renal vessels necrotizing granulomas of respiratory tract, necrotizing or granulomatous vasculitis, focal segmental necrotizing GN

c-ANCA positive

Wegener granulomatosis

26

[diagnosis]

recurrent oral aphthous ulcers, genital ulcers, uveitis, neutrophilic infiltration of vessels

small to medium sized vessels are affected

Behcet syndrome

27

[diagnosis]

strongly associated with cigarette smoking, small to medium vessel involvement, reynaud phenomenon, intermittent claudication, thrombosis with microabcesses

buerger disease

Thromboangitis obliterans

28

most important risk factor for lower extremity DVT

prolonged immobilization

29

[diagnosis]

migratory superficial vein thrombophlebitis in cancer patient

trosseau syndrome

30

[diagnosis]

lower extremity edema, superficial abdominal vein distention, massive proteinuria (if renal vein is involved)

IVC syndrome