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Flashcards in Environmental Pathology Deck (19)
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1

Ozone injures ___ type of pneumocytes via free radical formation

type I

2

cut off value for particulate matter that are more dangerous because it can travel to distal air spaces

<10um

3

CO inhibits what complex of the ETC

Complex IV or the Cyt C oxidase

4

Chronic CO poisoning affect which part of the CNS

basal ganglia and lenticular nuclei

5

heavy metal that inhibits ALA dehydratase and ferrochelatase

Lead

6

microcytic, hypochromic, anemia with hemolysis.

This is associated with ___ poisoning

lead

7

In lead poisoning among adults, which comes first, foot drop or wrist drop?

wrist drop.

lead causes peripheral demyelinating neuropathy

8

[heavymetal poisoning]

saturnine gout

lead

9

[heavymetal poisoning]

cerebral palsy, blindness, mental retardation, major CNS defect in utero exposure

methylmercury

minimata disease

10

"king of poisons"
"poison of kings"

Arsenic

11

Chronic exposure to this heavymetal can lead to hyperpigmentation and hyperkeratosis. usually affects palms and soles

Arsenic

12

[name the causative heavymetal agent]
osteoporosis
osteomalacia
renal disease

cadmium

itai-itai disease

13

what component of tobacco has the most carcinogenic effect

nitrosamine

14

Alcohol is metabolized by these enzymes to for acetaldehyde

CYP2E1 (MEOS
Alcohol dehydrogenase (main enzyme)
Catalase

15

[burn classification]

pink, mottled with blisters.

which layer/s of the skin is/are involved

Epidermis and dermis

2nd degree, partial thickness

16

[burn]

coagulative necrosis and inflammatory cell exudation are present in these burn stages

2nd and 3rd degree

17

[hyperthermia syndrome]

failure of CVS to compensate for hypovolemia from dehydration

heat exhaustion syndrome

18

this condition presents as heat-stroke-like symptoms after exposure to halothane

malignant hyperthermia

19

exposure of p53 in ionizing radiation causes its _____ (up/downregulation)

upregulation