Endocrine 6 Flashcards

1
Q

Compared to type 1 DM, choose the statements that MOST accurately describe type 2 DM (select 2).
a. peripheral sensitivity to insulin is reduced
b. it is more likely to cause hyperglycemia hyperosmolar syndrome
c. is usually associated with a thin body habitus
d. it is usually caused by an autoimmune response

A

a. peripheral sensitivity to insulin is reduced
b. it is more likely to cause hyperglycemic hyperosmolar syndrome

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2
Q

_________ and _________ don’t need insulin for glucose uptake

A

The brain and liver

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3
Q

With DM, although glucose is present in the bloodstream, it is

A

unable to enter many of the cells that require it which shifts metabolism towards protein catabolism and lipid oxidation

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4
Q

Type 1 DM is characterized by

A

a lack of insulin production (beta cell destruction)

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5
Q

Type 2 DM is characterized by

A

a relative lack of insulin+ insulin resistance

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6
Q

__________ describes a group of characteristics that are common to patients with DM or to those who are at higher risk of developing DM

A

Metabolic syndrome

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7
Q

Diagnostic criteria of metabolic syndrome includes

A

at least three of the following:
fasting plasma glucose >100-110 mg/dL
abdominal obesity (>40 in in men and >35 in women )
serum triglyceride level >150 mg/dL
serum HDL <40 mg/dL in men and <50 mg/dL in women
BP >130/85 mmHg

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8
Q

_____________ is more common with type 1 DM

A

diabetic ketoacidosis

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9
Q

Diabetic ketoacidosis is usually caused by

A

infection

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10
Q

Treatment of DKA includes

A

volume resuscitation, insulin, and potassium after acidosis subsides

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11
Q

_____________ is more common with type 2 DM

A

Hyperglycemic hyperosmolar state

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12
Q

Hyperglycemic hyperosmolar state is usually caused by

A

insulin resistance or inadequate insulin production

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13
Q

With HHS, glucose is typically

A

higher than DKA and metabolic acidosis is mild if present

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14
Q

Treatment of HHS includes

A

volume resuscitation, insulin, and electrolyte correction

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15
Q

Criteria for diagnosis of DM includes

A

fasting plasma glucose >126 mg/dL
random glucose level >200 mg/dL + classic symptoms
two hour plasma glucose >200 mg/dL during an oral glucose tolerance test
hemoglobin A1C> 6.5%

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16
Q

Classic symptom triad of DM is

A

polyuria
polydipsia
dehydration

17
Q

Treatment of type 1 DM includes

A

insulin (always required)

18
Q

Treatment of type 2 DM includes

A

weight reduction
dietary changes
oral hypoglycemic agents
insulin

19
Q

Symptoms of DKA may include

A

Kussmaul’s respirations d/t metabolic acidosis & acetone causes fruity-smelling breath

20
Q

The following factors can mask the signs of intraoperative hypoglycemia EXCEPT:
a. general anesthesia
b. propranolol
c. diabetic autonomic neuropathy
d. hydrochlorothiazide

A

d. hydrochlorothiazide

21
Q

_________ suggests an increased risk of difficult intubation in the DM patient

A

The prayer sign

22
Q

The DM patient may have reduced range of motion of the

A

AO joint

23
Q

DM patients are at risk of

A

aspiration
hypothermia
orthostatic hypotension

24
Q

___________ impairs the patient’s ability to mount a sympathetic response to hypovolemia & the cardio-depressant effects of anesthetic drugs

A

Diabetic autonomic neuropathy

25
Q

Hypoglycemia can be masked by

A

General anesthesia or beta-blockers

26
Q

When should surgery be scheduled for the Dm patient?

A

early in the day to prevent interruption of nutrition and hypoglycemic therapy

27
Q

Peripheral neuropathy usually begins in a

A

“stocking and glove” distribution

28
Q

Peripheral neuropathy is treated with

A

NSAIDs, antidepressants, and anticonvulsants

29
Q

Osmotic diuresis leads to

A

fluid and electrolyte abnormalities

30
Q

This fluid could cause hyperglycemia

A

Lactate in LR can be converted to glucose

31
Q

The DM patient should be assessed for

A

renal dysfunction

32
Q

Hyperglycemia worsens neurologic outcome after

A

ischemic brain injury

33
Q

Diabetic dysfunctions include

A

risk of dysrhythmias
reduced vagal tone– tachycardia
painless myocardial ischemia
diarrhea & constipation
regional anesthesia can worsen neurologic defects in the patient with diabetic polyneuropathy