Obstetrics 3 Flashcards

(62 cards)

1
Q

Fifteen minutes after a patient’s epidural as dosed, the patient becomes hypotensive and experiences respiratory arrest. What is the MOST likely etiology?
a. epidural catheter migration
b. loss of accessory respiratory muscle strength
c. subdural injection
d. eclampsia

A

C. subdural injection
this patient has experienced a total spinal

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2
Q

Describe the ways that a patient can develop a total spinal.

A

an epidural dose injected into the subarachnoid space
an epidural dose injected into the subdural space (s/sx may be delayed)
a single-shot spinal after a failed epidural block

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3
Q

Describe the treatment for a total spinal.

A

treatment is supportive and includes airway management, IVF, vasopressors, left uterine displacement, and leg elevation

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4
Q

___________________ will rule out subdural placement.

A

Neither catheter aspiration nor a test dose

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5
Q

Symptoms of a total spinal will include

A

dyspnea, difficulty phonating, and hypotension; loss of consciousness occurs as a result of cerebral hypoperfusion secondary to severe hypotension

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6
Q

Differential diagnosis for high spinal includes

A

anaphylactic shock, eclampsia, and amniotic fluid embolism

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7
Q

________ are causes of late decelerations.

A

maternal acidosis and preeclampsia

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8
Q

______ is consistent with early decelerations.

A

Fetal head compression

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9
Q

______ is a surrogate measure of fetal wellbeing.

A

Fetal heart rate

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10
Q

Fetal heart rate provides an indirect method to asess

A

fetal hypoxia and acidosis

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11
Q

_________ is a function of uterine and placental blood flow

A

Fetal oxygenation

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12
Q

The fetus responds to stress with

A

peripheral vasoconstriction, hypertension, and a baroreceptor-mediated reduction in heart rate

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13
Q

Normal fetal heart rate is

A

110-160

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14
Q

Bradycardic fetal heart rate is

A

<110

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15
Q

Tachycardic fetal heart rate is

A

> 160

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16
Q

What are the three types of fetal decelerations

A

early
late
variable

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17
Q

Which fetal decelerations put the fetus at risk?

A

late and variable

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18
Q

An absence of variability may indicate

A

fetal distress

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19
Q

Causes of lack of variability include

A

CNS depressants, hypoxemia, and acidosis

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20
Q

Variability is an indicator of

A

oxygenation, normal acid-base status
intact central nervous system
& SNS & PNS are functioning in a healthy way

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21
Q

Fetal causes of bradycardia include

A

asphyxia and acidosis

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22
Q

Maternal causes that lead to fetal bradycardia include

A

hypoxemia
drugs that decrease uteroplacental perfusion

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23
Q

Fetal causes of tachycardia include

A

hypoxemia
arrhythmias

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24
Q

Maternal causes that can lead to fetal tachycardia include

A

fever
choriomnionitis
atropine
ephedrine
terbutaline

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25
What is normal variability?
6-25 bpm
26
What is the mnemonic VEAL CHOP?
Variable decels: Cord compression Early decels: Head compression Accelerations: Ok or give oxygen Late decels: Placental insufficiency
27
According to the American College of Obstetrics and Gynecologists, which findings are predictive of poor fetal status? a. sinusoidal pattern b. no late or variable decelerations c. bradycardia without absence of baseline variability d. absent baseline variability
A & D.
28
Someone trained in fetal monitoring must monitor and document fetal status
before and after any anesthetic procedure
29
Describe Category 1 for evaluation of fetal heart rate.
suggest normal acid-base status with no threat to fetal oxygenation
30
Describe Category 2 for evaluation of fetal heart rate.
Is not 1 or 3 and cannot predict a normal or abnormal acid-base status
31
Describe Category 3 for evaluation of fetal heart rate.
suggest abnormal acid-base status with a significant threat to fetal oxygenation
32
Describe Category 1 findings.
Baseline heart rate between 110-160 moderate variability accelerations absent or present early decelerations absent or present No late or variable decelerations
33
Describe category 2 findings.
Bradycardia without the absence of baseline FHR variability tachycardia variable variability absent or minimal acceleration with fetal stimulation recurrent variable decelerations
34
Describe category 3 findings.
bradycardia absent baseline variability recurrent late deceleration recurrent variable deceleration sinusoidal pattern
35
The first sign of magnesium toxicity is
diminished deep tendon reflexes
36
Premature delivery is defined as delivery before
37 weeks gestation
37
The leading cause of perinatal morbidity and mortality is
premature delivery
38
The incidence of prematurity rises with
multiple gestations and premature rupture of membranes
39
Select fetal complications of prematurity include
respiratory distress syndrome, intraventricular hemorrhage, and NEC
40
_______ may be used to delay labor by suppressing uterine contractions (up to 24-48 hours).
Tocolytic agents
41
Examples of tocolytic agents include
beta-agonists magnesium sulfate calcium channel blockers nitric oxide donors
42
In the setting of preterm labor, ________ are given to hasten fetal lung maturity.
corticosteroids (betamethasone)
43
Tocolytic agents or corticosteroids are seldom given after
33 weeks of gestation
44
Side effects of beta agonists include
hyperglycemia resulting from glycogenolysis in the liver hypokalemia from intracellular potassium shift cross the placenta and may increase FHR newborn of a hyperglycemic mother is at risk of post-delivery hypoglycemia
45
What are examples of beta agonist tocolytics?
ritodrine and terbutaline
46
How do beta agonists prevent uterine contraction?
beta-2 stimulation increases intracellular cAMP--> turns on protein kinase, turns of MLCK--> relaxes the uterus also increases progesterone release which contributes to additional myometrial relaxation
47
How to calcium channel blockers work to prevent uterine contraction?
Blocks the influx of Ca+2 into the uterine muscle--> reduces Ca2+ release from the SR--> turns off myosin light-chain kinases--> relaxes uterine muscle
48
_______ is the first-line calcium channel blocker agent.
PO Nifedipine
49
Co-administration of calcium channel blockers with ______ can contribute to skeletal muscle weakness.
Magnesium
50
How do nitric oxide donors work?
nitric oxide is a vasodilator that is essential in maintaining smooth muscle tone increases cGMP--> turns off myosin light-chain kinases--> relaxes uterine muscle
51
_______ are rarely used due to hypotension.
Nitric oxide donors
52
How does magnesium sulfate work?
calcium antagonist--> relaxes smooth muscle by turning off MLCK in the vasuclature, airway, and uterus also hyperpolarizes excitable tissues
53
The ______ eliminate Mg2+, so mothers with ______ should be closely monitored
kidneys; renal insufficiency
54
What is the normal range of magnesium?
1.8-2.5 mg/dL
55
Hypomagnesemia can lead to
tetany, seizures, and dysrhythmias
56
We start to see diminished deep tendon reflexes at a magnesium level of
5-7 mg/dL
57
We see a loss of deep tendon reflexes, hypotension, EKG changes, and somnolence, at a magnesium of
7-12 mg/dL
58
We see respiratory depression, complete heart block, cardiac arrest, coma, and paralysis at a magnesium level of
>12 mg/dL
59
Additional side effects of hypermagnesemia include
skeletal muscle weakness (potentiates NMBD) pulmonary edema reduced responsiveness to ephedrine and phenylephrine
60
Treatment for hypermagnesemia includes
supportive measures diuretics (to facilitate excretion of Mg2+) IV calcium gluconate 1 g over 10 minutes (to antagonize Mg2+)
61
List 6 complications of premature delivery
NEC intraventricular hemorrhage respiratory insufficiency hypocalcemia hypoglycemia hyperbilirubinemia
62
Anesthetic considerations for the use of methergine include: a. IV administration is safe b. tocolysis c. administration of 0.2 mg d. risk of water intoxication
c. - should always be given IM