2/16 Flashcards
1
Q
Clomiphene
A
- Hypothalamus estrogen receptor blocker. Prevents negative feedback estrogen has on GnRH.
- this inc. FSH & LH production which stimulates ovulation.
- used to treat infertility due to anovulation.
- can cause visual disturbances.
2
Q
Danazol
A
-partial androgen agonist
-used for endometriosis & hereditary angioedema.
-
3
Q
Ticlopidine
A
- ADP receptor inhibitors
- this inhibits Gp2b/3a from being placed on receptor surface.
- watch out for neutropenia! (can present as mouth ulcers).
4
Q
Argatroban, bivalirudin
A
- derivatives of hirudin - the anticoagulant used by leeches.
- directly inhibit thrombin.
- used instead of heparin for pts w/HIT (heparin induced thrombocytopenia).
5
Q
Abciximab side effects
A
thrombocytopenia
6
Q
what causes 99% of mitral stenosis
A
rheumatic heart disease
7
Q
cladribine
A
- adenosine analog
- inhibits adenosine deaminase (adenosine buildup is toxic - like in SCID)
- treatment for hairy cell leukemia.
8
Q
Modafinil
A
- 1st line treatment for modafinil.
- non-amphetamine stimulant.
- P450 inducer
9
Q
De Quervain’s thyroiditis
A
- granulomas
- jaw pain, tender thyroid
- assoc. w/mumps & coxsackie
- potential early thyrotoxicosis.
10
Q
vemurafenib
A
- BRAF (V600E mutation specific) kinase inhibitor
- used for metastatic melanoma
11
Q
Whipple disease
A
- FOAMy WHIPPed cream in a CAN
- PAS (+) foamy macrophages in lamina propria
- Cardiac Sxs
- Arthralgias
- Neuro Sxs
12
Q
pudendal nerve block
-landmark?
A
- ischial spine.
- relieve pain of delivery
- S2-S4
13
Q
Scaphoid. Whats unique about its blood supply?
A
Retrograde blood supply.
-avascular necrosis common here.
14
Q
Dislocation of which bone can cause acute carpal tunnel?
A
lunate
15
Q
Guyon canal syndrome. Which nerve compressed?
A
ulnar nerve.
-commonly seen in cyclists due to pressure from handlebars.
