2/17 Flashcards

1
Q

Radial n.

  • roots
  • where are common injuries
  • classic sign
A
  • C5-T1
  • midshaft fx of humerus, compression of axilla.
  • wrist drop
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2
Q

Median n.

  • roots
  • where are common injuries
  • classic sign
A
  • C5-T1
  • Supracondylar fx of humerus (proximal lesion); carpal tunnel syndrome and wrist laceration (distal lesion).
  • Hand of benediction.
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3
Q

Ulnar n.

  • roots
  • where are common injuries
  • classic sign
A
  • C8-T1
  • medial epicondyle of humerus (funny bone). Hook of hamate. Guyon canal syndrome.
  • Ulnar claw on digit extension.
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4
Q

Which brachial plexus terminal nerves do NOT give branches in axilla or upper arm?

A

Median, Ulnar

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5
Q

What innervates:

-lateral flexor digitorum profundus & lateral 2 lumbricals.

A

median n.

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6
Q

What innervates:

-medial flexor digitorum profundus & medial 2 lumbricals.

A

ulnar n.

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7
Q

Atrophy of hypothenar eminence

A

-ulnar n. lesion

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8
Q

Is “clawing” seen w/distal or proximal lesions?

A

-distal

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9
Q

Actin are bound to __ line

A

Z

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10
Q

Myosin are bound to ___ line

A

M

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11
Q

I band =
H band =
A band =

A

I band = just actin
H band = just myosin
A band = entire length of myosin, stays the same.

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12
Q

PTH effect at low, intermittent levels.

A

-exerts anabolic effects.

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13
Q

Serum chemistry in osteoporosis

A

-normal serum chemistry!

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14
Q

What type of bone is lost in osteoporosis?

A

Trabecular (spongy) (cancellous)

-dorsolumbar vertebral bodies, neck of femur (50/50 trabecular & corticol)

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15
Q

What type of bone is lost in hyperparathyroidism?

A

corticol (your limbs)

-subperiosteal thinning.

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16
Q

denosumab

A
  • Tx for osteoporosis

- monoclonal antibody against RANKL

17
Q

osteopetrosis - can lead to marrow fibrosis

A
  • pancytopenia

- extarmedullary hematopoesis.

18
Q

Serum chemistry in osteomalacia

A
  • dec Calcium (leads to inc. PTH which leads to =>
  • dec. phosphate
  • inc. ALP (hyperactivity of osteoblasts).
19
Q

Serum chemistry in Pagets disease of bone.

-inc. risk for what cancer?

A
  • Ca, Phosphate, PTH = normal
  • inc. ALP (after lytic & mixed phase)
  • inc. risk of osteogenic sarcoma
20
Q

Pagets: inc. vascularity. How?

A
  • osteoclasts release cytokines that promote prolif of fibroblasts and endothelial cells.
  • AV shunts made
  • high output cardiac failure
21
Q

Most common location of avascular necrosis?

Which artery feed that location?

A

Femoral head, fed by medial circumflex femoral art.