3/22 neuro Flashcards Preview

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Flashcards in 3/22 neuro Deck (109)
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1

Short acting benzos?
-mnemonic?

TOM acts fast
-triazolam
-oxazepam
-midazolam

*also alprazolam. AL bundy has a short fuse.

2

Essential tremor
-Tx:

propanolol
-2nd line = primidone.

3

3 major types of glial cells

astrocytes, oligodendrocytes, microglia

4

astrocytes & oligodendros
-derived from what tissue?

neuroectoderm

5

which hypoT nucleus maintains circadian rhythm?
-mnemonic?

suprachiasmatic nucleus
-hard to be "super charismatic" when you have jet lag.

6

All sensory information goes through thalamus except:

olfaction

7

When a pt needs IV ABxs, can oral ABxs be a good enough substitute?

no
-oral ABxs do not adequately penetrate the CSF.

8

heroin withdrawal
-key Sxs:

dilated pupils
yawning
lacrimation

9

Alcohol & benzo withdrawal
-key Sxs:

tachy
seizures

10

nicotine withdrawal
-key Sxs:

inc. appetite

11

Seizures
-opioid or alcohol withdrawal?

alcohol withdrawal can produce seizures, opioid withdrawal does NOT.

*benzo withdrawal can also lead to seizures.

12

nicotinic receptor
-how many ACh need to bind for channel to open?

2

13

chlorpromazine
-high or low potency?

low potency antipsychotic

14

fluphenazine
-high or low potency?

high potency antipsychotic

15

entacapone
-mech?

peripheral COMT inhibitors, prevent L-DOPA degradation, increased dopamine availability.

16

entacapone vs tolcapone
-difference?

Entacapone inhibits peripheral COMT while tolcapone inhibits both central & peripheral COMT.

17

MAO-B
-degrades what?

dopamine

18

MAO-A
-degrades what?

NE & serotonin

19

Which receptor causes mydriasis?

alpha1

20

What nerve inn. all the muscles of mastication?

V3 (mandibular) of the trigeminal

21

which muscle opens the jaw?

lateral pterygoid

22

Mandibular n. (V3, trigeminal)
-exits skull through which foramen?

foramen ovale

23

Maxillary n. (V2, trigeminal)
-exits skull through which foramen?

foramen rotundum

24

TCAs
-blockade of what leads to arrythmias?

cardiac fast sodium channels

*also keep in mind, blockade of muscarinic receptors can also cause tachy.

25

TCAs have inhibitory effects on what receptors?

-NE & serotonin reuptake
-muscarinic
-alpha-1
-histamine
-cardiac fast Na channels

26

Whats the most common cause of death in pts w/anti-depressant toxicity?

TCAs inhibit cardiac fast sodium channels resulting in arrythmias.

27

ant pit
-derived from what tissue?

rathke pouch = surface ectoderm

28

post pit.
-derived from what tissue?

neural tube (which is from ectoderm).

29

Alar plate
-ventral or dorsal?
-motor or sensory?

(dorsal): sensory

30

Basal plate
-ventral or dorsal?
-motor or sensory?

(ventral): motor