3/27&28 psych Flashcards

1
Q

cofactor for glutamate & GABA transaminase?

A

B6

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2
Q

fexofenadine

-what is it?

A

2nd gen. H1 blocker

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3
Q

2nd get H1 blockers

  • suffix?
  • exception?
A
  • adine

- cetirizine

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4
Q

cetirizine

-what is it?

A

2nd get H1 blocker

-zertec

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5
Q

promethazine

-what is it?

A

1st gen H1 blocker

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6
Q

Buspirone

-pros?

A

Does not cause sedation, addiction, or tolerance.

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7
Q

DOPA

-short for what?

A

dihydroxyphenylalanine

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8
Q

rate-limiting step in catecholamine synth

A

tyrosine hydroxylase

-tyrosine => DOPA

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9
Q

reserpine

  • mech:
  • use:
A

-inhibits dopamine entry into pre-synaptic vesicles,
effectively causing a chemical sympathectomy.
-reduces BP & HR.

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10
Q

Ciliary muscle under what control?

A

Mostly muscarinic control.

-slight beta-2 control.

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11
Q

Opioids depress respiration by reducing responsiveness of central respiratory centers to ____

A

CO2

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12
Q

Highest risk age-group for suicide:

A

45-64

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13
Q

reuptake of Ca back into SR

-ATP dep?

A

yes, its ATP dependent. (ryanodine receptors).

  • this is crucial part of malignant hyperthermia, burning all that ATP generates heat!
  • high temp will induce muscle damage.
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14
Q

malignant hyperthermia

-how is the muscle damaged?

A
  • low ATP & high temp from burning so much ATP damages muscle cells.
  • you burn a lot of ATP trying to put that Ca back into the SR w/ryanodine receptors.
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15
Q

trigeminal neuralgia

-Tx:

A

carbamazepine

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16
Q

reduction of portal venous pressure to prevent variceal bleed

A

propranolol

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17
Q

Most feared side effect of carbamazepine

A

agranulocytosis

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18
Q

If a 3 year old doesn’t play cooperatively w/other, is that a social development delay?

A

No. At 3 yo children are expected to play in parallel w/other kids, not cooperatively.

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19
Q

phenelzine

-what is it?

A

MAO inhibitor

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20
Q

Depressed pt who has hypertensive crisis after a wine/cheese party.

A

MAO-inhibitor / tyramine crisis.

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21
Q

Classic conditioning v Operant conditioning

-which one is dealing w/involuntary responses & which w/voluntary?

A
classic = involuntary (ie. salivating).
operant = voluntary (ie. behavior training).
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22
Q

Operant conditioning:

-what is “extinction”?

A
  • Discontinuation of reinforcement (positive or negative) eventually eliminates behavior.
  • ie. a child who climbs under his desk, a response which has been reinforced by attention, is subsequently ignored until the attention-seeking behavior no longer occurs.
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23
Q

Transference

-define:

A

Patient projects feelings about formative or other important persons onto physician (e.g., psychiatrist is seen as parent).

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24
Q

Countertransference

-define:

A

-Doctor projects feelings about formative or other important persons onto patient (e.g., patient reminds physician of younger sibling).

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25
Q

Dissociation

  • mature or immature ego defense?
  • define:
A

-immature
-Temporary, drastic change in personality, memory, consciousness, or motor behavior to avoid emotional stress.
-Extreme forms can result in dissociative identity
disorder (multiple personality disorder).

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26
Q

Denial

-mature or immature ego defense?

A

immature

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27
Q

Ego defenses

-conscious or unconscious?

A

unconscious

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28
Q

Displacement

  • mature or immature ego defense?
  • define:
  • example:
A

-immature
-transfer of an impulse toward a safer & less
distressful object.
-husband yelling at his dog after argument w/wife.

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29
Q

Fixation

  • mature or immature ego defense?
  • define:
  • example:
A

-immature
-Partially remaining at a more childish level of
development (vs. regression).
-Men fixating on sports games.

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30
Q

Identification

-mature or immature ego defense?

A

immature

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31
Q

Isolation

  • mature or immature ego defense?
  • define:
  • example:
A
  • immature
  • Separating feelings from ideas and events.
  • Describing murder in graphic detail with no emotional response.
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32
Q

Fantasy

-mature or immature ego defense?

A

immature

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33
Q

Projection

  • mature or immature ego defense?
  • define:
  • example:
A

-immature
-projecting your “unacceptable” feelings onto someone
else.
-A man who wants another woman thinks his wife is cheating on him.

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34
Q

Rationalization

-mature or immature ego defense?

A

immature

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35
Q

Regression

  • mature or immature ego defense?
  • example:
A

-immature
-bedwetting in a previously toilet-trained child
when hospitalized

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36
Q

Repression

  • mature or immature ego defense?
  • voluntary or involuntary?
A

immature

-involuntary

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37
Q

Splitting

  • mature or immature ego defense?
  • commonly seen in which disorder?
A
  • immature

- Commonly seen in borderline personality disorder.

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38
Q

Altruism

-mature or immature ego defense?

A

mature

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39
Q

Humor

-mature or immature ego defense?

A

mature

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40
Q

Sublimation

  • mature or immature ego defense?
  • define:
  • example:
A
  • mature
  • Replacing an unacceptable wish with a course of action that is similar to the wish but does not conflict with one’s value system (vs. rxn formation).
  • Teenager’s aggression toward his father is redirected to perform well in sports.
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41
Q

Reaction formation

  • mature or immature ego defense?
  • define:
  • example:
A

-immature
-a person does the opposite of what he/she desires.
Usually a short-term immature response that eventually
breaks down. You feel bad about this desire.
-a former smoker vigorously enforcing a smoking ban.

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42
Q

Suppression

-mature or immature ego defense?

A

mature

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43
Q

mature ego defenses

-mnemonic:

A

Mature adults wear a SASH:

-Sublimation, Altruism, Suppression, Humor.

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44
Q

Anaclitic depression

  • what is it?
  • what is it a result of?
A
  • infant withdrawn/unresponsive.

- result of infant deprivation.

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45
Q

Infant deprivation

  • after how long are changes irreversible?
  • what can severe deprivation result in?
A

> 6 mo

-Severe deprivation can result in infant death.

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46
Q

Sexual abuse of child

  • peak age range?
  • abuser?
A
  • 9-12

- Known to victim, usually male

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47
Q

Physical abuse of child

  • peak age range?
  • abuser?
A

< 3 yo

-Usually biological mother

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48
Q

ADHD

  • onset before age __
  • intelligence level?
  • associated w/what physical brain abnormality?
A
  • 12
  • normal intelligence but commonly coexists w/difficulties in school.
  • Associated with  frontal lobe volume/metabolism.
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49
Q

atomoxetine

  • what is it?
  • whats it used for?
A
  • NE reuptake inhibitor.

- ADHD

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50
Q

Conduct disorder

  • age range?
  • will most likely progress to what?
A
  • < 18yo

- After age 18, many of these patients will meet criteria for diagnosis of antisocial personality disorder.

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51
Q

Oppositional defiant disorder

-define:

A

Enduring pattern of hostile, defiant behavior toward authority figures in the absence of serious violations of social norms.

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52
Q

Tourette syndrome

  • onset of age:
  • how long must it last for a Dx?
  • Tx:
A
  • < 18 yo
  • > 1 year
  • antipsychotics and behavioral therapy.
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53
Q

Separation anxiety disorder

  • common age of onset?
  • Tx:
A
  • 7-9 yrs

- SSRIs and relaxation techniques/behavioral interventions.

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54
Q

Pervasive developmental disorders

  • define:
  • name 2 of them:
A
  • Delays in the development of socialization and communication skills.
  • Autism spectrum disorder, Rette disorder.
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55
Q

Do autistic children get separation anxiety?

A

-no separation anxiety b/c there was no attachment

in the first place.

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56
Q

Rett disorder

  • inheritance pattern:
  • seen in which pt population:
A
  • X-linked recessive

- Seen in GIRLS bc boys w/disease die in utero.

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57
Q

Rett disorder

-Sxs:

A

-loss of development, loss of verbal abilities, intellectual disability, ataxia, and stereotyped hand-wringing.

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58
Q

Anxiety: NT levels

  • NE:
  • 5-HT:
  • GABA:
A
  • inc. NE
  • dec. GABA
  • dec. 5-HT
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59
Q

Huntingtons disease: NT levels

  • GABA:
  • ACh:
  • dopamine:
A
  • dec. GABA
  • dec. ACh
  • inc. dopamine
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60
Q

Parkinson disease: NT levels

  • dopamine:
  • ACh:
  • 5-HT:
A
  • dec. dopamine
  • inc. ACh
  • inc. serotonin
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61
Q

Parkinsons disease

-serotonin level?

A

-inc. serotonin

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62
Q

Schizophrenia

-which NT level is off the most?

A

inc. dopamine

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63
Q

Orientation

-what 3 things do they check and in which order are they lost?

A

Order of loss:
1st—time
2nd—place
last—person.

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64
Q

Dissociative amnesia

-what is it?

A

Inability to recall important personal information, usually subsequent to severe trauma or stress.
-May be accompanied by dissociative fugue.

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65
Q

Dissociative fugue

A

Abrupt travel or wandering during a period of

dissociative amnesia, associated with traumatic circumstances.

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66
Q

Cognitive disorder

  • define:
  • what two syndromes does are encompassed?
A
  • Significant change in cognition: memory, attention, language, judgment.
  • Includes delirium and dementia.
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67
Q

“Waxing and waning” level of consciousness
with acute onset.
-delirium or dementia?

A

Delirium

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68
Q

Delirium vs Dementia

  • onset:
  • consciousness:
  • course:
A
  • Delirium = acute = impaired consciousness = fluctuating

- Dementia = gradual (months to years) = intact consciousness = progressive

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69
Q

Delirium vs Dementia

-reversible?

A
Delirium = reversible
Dementia = irreversible
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70
Q

Delirium

-check drugs for which type of effect?

A

-anticholinergic effects.

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71
Q

Delirium

  • hallucinations?
  • if so what type?
A

hallucinations = often visual.

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72
Q

Delirium

  • normal or abnormal EEG?
  • Tx:
A
  • Abnormal EEG.

- Optimize brain condition (O2, hydration, pain, etc.) & ƒ antipsychotics (mainly haloperidol).

73
Q

Normal Pressure Hydrocephalus

-is the dementia reversible?

A

-yes, reversible.

74
Q

Hypothyroidism

-is the dementia reversible?

A

-yes, reversible.

75
Q

Neurosyphilis

-is the dementia reversible?

A

-yes, reversible.

76
Q

B12 deficiency

-is the dementia reversible?

A

-yes, reversible.

77
Q

Dementia

  • normal or abnormal EEG?
  • Tx:
A
  • normal EEG.

- no Tx

78
Q

Chronic substance abuse

-is the dementia reversible?

A

-No.

79
Q

Creutzfeldt-Jakob disease

-is the dementia reversible?

A

-No.

80
Q

Lewy body dementia

-is the dementia reversible?

A

-No.

81
Q

Psychosis

  • definition:
  • characterized by:
A
  • A distorted perception of reality.

- Delusions, hallucinations, &/or disorganized thinking.

82
Q

Visual hallucinations

-More commonly a feature of what type of illness?

A

Medical illness (ie. drug intox).

83
Q

Auditory hallucinations

-More commonly a feature of what type of illness?

A

Psychiatric illness (e.g., schizophrenia).

84
Q

Tactile hallucinations

-Commonly seen in what?

A
  • Common in alcohol withdrawal (e.g., formication—the sensation of bugs crawling on one’s skin).
  • Also seen in cocaine abusers (“cocaine crawlies”).
85
Q

HypnaGOgic hallucinations

-when do they occur?

A

Occurs while GOing to sleep.

86
Q

HypnoPOMPic hallucinations

-when do they occur?

A

Occurs while waking from sleep (“POMPous upon awakening”).

87
Q

Schizophrenia

  • Sxs have to last for how long?
  • chemical imbalance?
  • inc or dec. dendritic branching?
A

> 6 mo.

  • inc. dopamine
  • dec. dendritic branching
88
Q

Schizophrenia

-Dx req 2 of the following:

A
  • Delusions
  • Hallucinations—often auditory
  • Disorganized speech (loose associations)
  • Disorganized or catatonic behavior
  • “Negative symptoms”—flat affect, social withdrawal, lack of motivation, lack of speech or thought
89
Q

Schizophrenic Sxs for < 1 mo:

  • defined as what?
  • will pt fully recover?
A
  • Brief psychotic disorder

- pt will return to full functionality.

90
Q

Schizophrenic Sxs for 1-6 mo:

-defined as what?

A

Schizophreniform disorder

91
Q

Schizoaffective disorder

  • what needs to happen to Dx this?
  • 2 subtypes:
A

-At least 2 weeks of stable mood w/psychotic symptoms, plus a major depressive, manic, or mixed (both) episode. -2 subtypes: bipolar or depressive.

92
Q

Delusional disorder

  • has to last how long?
  • describe it:
A

> 1 mo

-typically have a persistent, over-riding delusion w/a specific theme. Behavior is not obviously bizarre.

93
Q

Dissociative disorders

-what are they?

A
  • conditions that involve disruptions or breakdowns of memory, awareness, identity, or perception.
  • People with dissociative disorders use dissociation, an immature defense mechanism, pathologically and involuntarily.
94
Q

Dissociative identity disorder

-formerly known as?

A

-Multiple personality disorder

-

95
Q

Mood disorders

  • what are they?
  • name some of them:
A
  • Abnormal range of moods or internal emotional states and loss of control over them.
  • major depressive disorder
  • bipolar disorder
  • dysthymic disorder
  • cyclothymic disorder
96
Q

Mood disorders

-can psychotic features be present?

A

Yes.

97
Q

Schizophrenia

-when does it present: men & women?

A
  • Presents earlier in men.
  • men: late teens to early 20s
  • women: late 20s to early 30s
98
Q

Manic episode

-by definition, how long does it have to last?

A

At least 1 week.

99
Q

Manic episode

  • requires hospitalization or at least 3 of the following:
  • mnemonic?
A

DIG FAST

  • Distractibility
  • Irresponsibility—seeks pleasure without regard to consequences (hedonistic).
  • Grandiosity—inflated self-esteem
  • Flight of ideas—racing thoughts
  • Inc. in goal-directed Activity/psychomotor Agitation
  • dec. need for Sleep
  • Talkativeness or pressured speech
100
Q

Hypomanic episode

  • what is it?
  • are there psychotic features?
  • how long does it last?
A
  • Like manic episode except mood disturbance is not severe enough to cause marked impairment in social and/or occupational functioning or to necessitate hospitalization.
  • No psychotic features.
  • Lasts at least 4 consecutive days.
101
Q

Bipolar disorder

-Bipolar I =

A

-presence of at least 1 manic episode with or without a hypomanic or depressive episode.

102
Q

Bipolar disorder

-Bipolar II

A

-defined by the presence of a hypomanic and a depressive episode.

103
Q

Bipolar disorder

-is pts mood ever normal?

A

-Patient’s mood and functioning usually return to normal between episodes.

104
Q

Should you use anti-depressants to treat bipolar pts?

A

No - it can lead to mania.

-you dont want to increase their dopamine!

105
Q

Cyclothymic disorder

  • what is it?
  • how long does it have to last by definition?
A

-dysthymia and hypomania; milder form of bipolar disorder -Lasting at least 2 years.

106
Q

dysthymia =

A

-mild but chronic depression.

107
Q

Major depressive disorder

-how long do episodes have to be, minimally?

A

2 or more weeks.

108
Q

Major depressive disorder

  • have to have 2 of the 9 Sxs
  • name the Sxs:
  • mnemonic:
A

SIG E CAPS:

  • Sleep disturbance
  • loss of Interest (anhedonia)
  • Guilt or feelings of worthlessness
  • Energy loss and fatigue
  • Concentration problems
  • Appetite/weight changes
  • Psychomotor retardation or agitation
  • Suicidal ideations
109
Q

Major depressive disorder: sleep changes

  • slow wave sleep?
  • REM latency
  • total REM sleep
  • nighttime awakening?
A
  • dec. slow wave sleep
  • dec. REM latency
  • inc total REM sleep
  • inc. nighttime awakenings
  • early morning awakenings.
110
Q

Major depressive disorder: sleep changes

-whats a good screening question?

A

Do they have early-morning awakenings.

111
Q

Atypical depression

-difference from typical depression?

A

-mood reactivity
-“reversed” vegetative symptoms (weight gain).
-leaden paralysis (heavy feeling in arms and legs).
-

112
Q

mood reactivity

  • define
  • what disorder do you see it in?
A
  • being able to experience improved mood in response to positive events, albeit briefly.
  • atypical depression.
113
Q

Maternal (postpartum) “blues”

  • how long after delivery does it begin?
  • how long does it last?
A
  • starts 2-3 days after delivery.

- usually resolves w/in 10 days.

114
Q

Postpartum depression

  • how long after delivery does it begin?
  • how long does it last?
A
  • starts within 4 weeks of delivery.

- lasts 2 weeks to a year or more.

115
Q

Postpartum psychosis

  • how long after delivery does it begin?
  • how long does it last?
A
  • starts within 4 weeks of delivery.

- lasts btwn 4-6 weeks.

116
Q

If a pt complains about another doctor to you, what should you tell them?

A

I understand you’re upset, but I suggest you speak directly to Mr. Smith about your concerns.

  • If the pt is uncomfortable doing so, the hospital has pt advocates who can address their concerns for them.
  • If the pt has a problem with someone in your office staff, tell the pt you will speak to that individual.
117
Q

Bupropion

-C/I in which pts? why?

A
  • Can cause seizures in bulimic w/purging or anorexia w/purging.
  • bupropion reduces seizure threshold.
  • due to their electrolyte imbalances from purging.
118
Q

melanosis coli

-what is it?

A

Blackened area on the colon as a result of laxative abuse.

119
Q

Which drug can be used in anorexics who have depression w/o fear of them losing more weight?

A

Mirtazapine

120
Q

nortriptyline

-what is it?

A

TCA

121
Q

If baby will die w/o C section but coherent mother refuses C section & admissions note also states she doesn’t want C section - do you perform the C section to save the babies life?

A

No

-Even tho woman is pregnant, it does not limit the requirement of informed consent for a procedure.

122
Q

Loss to follow-up

-what sort of bias is this?

A

Part of selection bias.

123
Q

Sampling bias leads to a lack of ______ validity.

A

external

124
Q

What age does babinsky reflex disappear?

A

12 months

125
Q

At what age can baby climb stairs alone?

A

18 months

126
Q

If a pt is calling w/anxiety about something - do you deal with it then or tell her to write down her questions and talk about it at appointment?

A

You deal with it then.

127
Q

Does the good samaritan law protect you from legal action?

A

No

-you can get sued if the care provided was negligent and results in injury. Also if you didn’t use standard of care.

128
Q

Which recreational drug can produce vertical & horizontal nystagmus?

A

PCP

129
Q

TCA OD

-Tx:

A

sodium bicarb for CV tox.

130
Q

PCP OD

-Tx:

A

benzos & anti-psychotics

131
Q

PTSD

-Tx:

A

SSRI

-fluoxetine.

132
Q

BMI =

A

BMI = (weight in kg)/ [(height in m)^2]

133
Q

Late-look bias

-what is it?

A
  • info gathered at inappropriate time

- sampling people w/milder form of disease bc those w/severe form have already died from it.

134
Q

whats a type 2 error

A

Finding no difference when in fact there is one.

-False negative

135
Q

false negative rate of a test

-alpha or beta?

A

beta

136
Q

Normal grief

-how long does it last?

A

6-12 months

137
Q

Simple hallucinations during grieving

-normal or pathological?

A

normal

-ie. hearing name called.

138
Q

Electroconvulsive therapy

-whats it used for?

A

1)major depressive disorder refractory to other treatment. 2)pregnant women with major depressive disorder.

139
Q

Is access to firearms a risk for suicide completion?

A

Yes

140
Q

Anxiety disorder

-encompasses which 3 disorders?

A

Includes panic disorder, phobias, and generalized anxiety disorder.

141
Q

Panic attack

-how long after it starts does it usually peak?

A

10 min

142
Q

Panic disorder

-Dx requires what?

A
  • Dx reqs attack followed by 1 month (or more) of 1 (or more) of the following:
  • persistent concern of additional attacks.
  • worrying about consequences of the attack.
  • behavioral change related to attacks.
143
Q

Panic attack

  • what acid/base disorder do you get?
  • what will bicarb be?
A
  • respiratory alkalosis due to hyperventilation.

- bicarb is normal bc its an acute attack.

144
Q

Shortness of breath

  • aka?
  • does it cause a resp acidosis or alkalosis?
A

dyspnea

  • resp alkalosis bc you’re breathing so fast.
  • is this true? i dont know.
145
Q

Social anxiety disorder

-Tx:

A

SSRI

146
Q

Generalized anxiety disorder

-how long does it have to last to make the Dx?

A

> 6 months

147
Q

Generalized anxiety disorder

-Tx:

A

SSRI, SNRI, buspirone.

148
Q

Adjustment disorder

  • branch of what disease?
  • what is it?
  • how long does it have to last to make the Dx?
A
  • Generalized anxiety disorder
  • emotional symptoms (anxiety, depression) causing impairment following an identifiable psychosocial stressor.
  • < 6 months (> 6 months in presence of chronic stressor).
149
Q

Obsessive-compulsive disorder

-associated w/what other disease?

A

-Associated with Tourette disorder.

150
Q

Obsessive-compulsive disorder

-egodystonic or egosyntonic?

A

-egodystonic (vs. obsessive-compulsive personality disorder).

151
Q

Pt. w/repeated plastic surgeries: may have what disease?

A

Body dysmorphic disorder

-preoccupation with minor or imagined defect in appearance, leading to significant emotional distress.

152
Q

PTSD

-how long it last to make the Dx?

A

> 1 month

-leads to avoidance of stimuli.

153
Q

PTSD

-Tx:

A

-psychotherapy, SSRIs.

154
Q

What do you call PTSD that lasts btwn 3 days and 1 month?

A

Acute stress disorder

155
Q

Malingering

-define

A

Patient consciously fakes, profoundly exaggerates, or claims to have a disorder in order to attain a specific 2° (external) gain (e.g., avoiding work, obtaining compensation).

156
Q

Somatoform disorders

-is there a conscious attempt to deceive?

A

no

157
Q

Factitious disorder

-is there a conscious attempt to deceive?

A

yes

158
Q

Living will vs. durable power of attorney

-which supercedes?

A

Durable power of attorney supercedes

159
Q

Does normal grief include suicidal thoughts?

A

No

160
Q

Jehovah fitness child in emergency and needs blood. Parents refuse. Do you give him the blood?

A

Yes.

161
Q

Bipolar I or II

-which has a manic episode?

A

Bipolar I has manic episode.

-bipolar I can be Dx after a single manic episode.

162
Q

Non-random assignment to study groups

-what type of bias?

A

Selection bias.

163
Q

Group of subjects is not representative of the population of interest
-what type of bias?

A

Sampling bias.

164
Q

Premature delivery/labor: why would you want to stop labor?

A

So you can give penicillin & steroids to prevent group B strep & NRDS.

165
Q

Prematurity

-limit of viability?

A

24 weeks.

166
Q

tocolysis

-define

A

stopping labor.

-ie. terbutaline, ritodrine, magnesium sulfate.

167
Q

tocolysis is attempted until how many weeks?

A

attempted for all babies < 34 weeks.

168
Q

Stack six blocks, 2 word sentences, use utensils

-how old?

A

2 yo

169
Q

Case control vs cohort

-make sure to pay attention to what?

A

Pay attention to wording of the question.

  • If they wanna know what the risks of “developing” something is - that means prospective study which means cohort study.
  • pay attention to tense of verbs.
170
Q

Alcoholic withdrawal Tx:

-pt has cirrhosis

A

Out The Liver
Oxazepam, temazepam, lorazepam
*1st line = lorazepam.

171
Q

Tuberous sclerosis

-associated w/which mental disability?

A

Autism.

172
Q

Schizoid v avoidant

-which one desires relationships w/others?

A

avoidant

173
Q

Hawthorne effect

  • what is it?
  • mnemonic?
A
  • groups who know they’re being studied behave differently than they would otherwise
  • being on the streets in Hawthorne knowing the cops are watching you. The criminals behave differently.
174
Q

antisocial personality disorder

-associated w/which comorbidity?

A

substance abuse

175
Q

Changes in elderly:

  • more or less fat?
  • more or less REM & slow wave sleep?
A
  • more fat, less muscle.

- less REM & slow wave sleep.

176
Q

Disorganized speech / loose connections - aka how kendall talks when he’s manic.
-part of what umbrella term?

A

Part of psychosis.

177
Q

Can psychotic features be present in mood disorders (ie. bipolarism)?
-example?

A

Yes.
-Like Kendall. He has bipolar disorder but also psychotic features like loose association (disorganized speech). He may also have hallucinations & delusions - who knows.

178
Q

Baby rolls over w/o assistance

-how old?

A

6 mo.

179
Q

Schizo

-inc. dopamine in which pathway?

A

mesolimbic system