Complications of Liver Disease Flashcards Preview

Digestive, Endocrine, and Metabolic Systems > Complications of Liver Disease > Flashcards

Flashcards in Complications of Liver Disease Deck (10):
1

True or false: a biopsy of someone with hepatorenal syndrome will demonstrate thickened sub-epithelial membrane.

False. There are no structural effects in the kidneys of someone with hepatorenal syndrome.

2

There are two types of hepatorenal syndrome. Which is more severe?

Type I

3

What things are needed for a diagnosis of hepatorenal syndrome?

- portal hypertension
- creatinine greater than 1.5 mg/dl or clearance less than 40 ml/min
- absence of shock, bacterial infection, or nephrotoxic drugs
- absence of excessive GI or renal fluid loss
- no improvement in renal function after 1.5 l of fluid
- urinary protein less than 500 mg/dl
- ascites
- hyponatremia

4

What is SBP?

Spontaneous bacterial peritonitis – the most common infection in cirrhotic patients

5

An ascites PMN count greater than 250/mL indicates __________.

SBP

6

The three most common organisms that cause SBP are _____________.

E. coli, Streptococcus and Klebsiella

7

SBP frequently ___________.

recurs

8

True or false: ammonia elevation is required for a diagnosis of hepatic encephalopathy.

False. Ammonia levels are notoriously unreliable.

9

Lactulose helps treat hepatic encephalopathy by ___________.

acidifying the stool, which then absorbs NH3

10

Why is HLA testing not needed for liver transplantation?

Because the liver is not immunologically active, so blood testing is the only requirement

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