Hypothalamic and Pituitary Pharmacology Flashcards Preview

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Flashcards in Hypothalamic and Pituitary Pharmacology Deck (15):
1

Growth hormone (somatotrophin) is given to children with ______________.

poor growth due to Turner syndrome or Prader-Willi

2

In those with acromegaly who do not want surgery, ______________ are the preferred medical treatment.

somatostatin analogs

3

Somatostatin activates a ______________ receptor.

Gi/o

4

In addition to antipsychotics, ___________ can also cause hyperprolactinemia.

estrogen

5

ADH has two effects. Which one occurs at lower doses?

The antidiuretic effect occurs at lower doses. The vasopressor effect (on V1 receptors) occurs at higher doses.

6

All V2 antagonists end with the suffix __________.

-vaptan

7

In general, use of GH for "anti-aging" is associated with _______________.

minimal changes in body composition and increased risk of adverse effects; there is not much research on this, however

8

Dopamine agonists are not as effective as ___________ in treating gigantism.

somatostatins

9

ADH must be administered _______________.

parenterally (IV, IM, or intranasal)

10

Release of _________ can be inhibited by alcohol.

ADH

11

In someone with nephrogenic diabetes insipidus, thiazides cause ________________.

paradoxical antidiuresis

12

Growth hormone binds to what type of receptor?

JAK-STAT

13

You'll need to treat someone with ________ dwarfism with IGF-1 instead of Somatropin.

Laron

14

_____________ can cause increases in intracranial pressure.

Growth hormone

15

_______________ decrease the release of TSH.

Somatostatin and T4/T3

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